2-keto-4-methylthiobutyric acid has been researched along with Hepatic Encephalopathy in 1 studies
2-keto-4-methylthiobutyric acid: RN given refers to parent cpd; structure
4-methylthio-2-oxobutanoic acid : A 2-oxo monocarboxylic acid derived from L-methionine via the action of methionine transaminase.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The concentrations of methanethiol-mixed disulfides, methionine, 4-methylthio-2-oxobutyrate and ammonia were measured in patients with different stages of hepatic encephalopathy, in patients with chronic kidney failure and in healthy subjects." | 3.68 | The role of methanethiol in the pathogenesis of hepatic encephalopathy. ( Blom, HJ; Ferenci, P; Grimm, G; Tangerman, A; Yap, SH, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blom, HJ | 1 |
| Ferenci, P | 1 |
| Grimm, G | 1 |
| Yap, SH | 1 |
| Tangerman, A | 1 |
1 other study available for 2-keto-4-methylthiobutyric acid and Hepatic Encephalopathy
| Article | Year |
|---|---|
The role of methanethiol in the pathogenesis of hepatic encephalopathy.
Topics: Adult; Ammonia; Disulfides; Female; Hepatic Encephalopathy; Humans; Liver Diseases; Male; Methionine | 1991 |