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2-keto-4-methylthiobutyric acid and Carcinoma, Ovarian Epithelial

2-keto-4-methylthiobutyric acid has been researched along with Carcinoma, Ovarian Epithelial in 1 studies

2-keto-4-methylthiobutyric acid: RN given refers to parent cpd; structure
4-methylthio-2-oxobutanoic acid : A 2-oxo monocarboxylic acid derived from L-methionine via the action of methionine transaminase.

Carcinoma, Ovarian Epithelial: A malignant neoplasm that originates in cells on the surface EPITHELIUM of the ovary and is the most common form of ovarian cancer. There are five histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Mutations in BRCA1, OPCML, PRKN, PIK3CA, AKT1, CTNNB1, RRAS2, and CDH1 genes are associated with this cancer.

Research Excerpts

ExcerptRelevanceReference
"The CtBP2 inhibitor MTOB suppressed ovarian cancer cell survival in a CtBP2-dependent manner."1.39BRCA1 expression is epigenetically repressed in sporadic ovarian cancer cells by overexpression of C-terminal binding protein 2. ( Berkowitz, RS; Crum, C; Gali, R; He, H; Liu, S; May, T; Ng, SK; Ng, SW; Shoni, M; Yang, J, 2013)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
May, T1
Yang, J1
Shoni, M1
Liu, S1
He, H1
Gali, R1
Ng, SK1
Crum, C1
Berkowitz, RS1
Ng, SW1

Other Studies

1 other study available for 2-keto-4-methylthiobutyric acid and Carcinoma, Ovarian Epithelial

ArticleYear
BRCA1 expression is epigenetically repressed in sporadic ovarian cancer cells by overexpression of C-terminal binding protein 2.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:6

    Topics: Alcohol Oxidoreductases; BRCA1 Protein; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Surviv

2013