2-hydroxysaclofen has been researched along with Cocaine-Related Disorders in 1 studies
2-hydroxysaclofen: structure given in first source
Cocaine-Related Disorders: Disorders related or resulting from use of cocaine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Separate groups of rats received bilateral intra-VTA injections of the GABA-A antagonist picrotoxin (34 ng/side, n = 7; 68 ng/side, n = 8), GABA-A agonist muscimol (14 ng/side, n = 8), GABA-B agonist baclofen (56 ng/side, n = 7; 100 ng/side, n = 6), picrotoxin (68 ng/side) co-injected with the GABA-B antagonist 2-hydroxysaclofen (100 ng/side, n = 7; 2 microg/side, n = 8) or artificial cerebrospinal fluid (aCSF, n = 6) to assess the effects of the various compounds on the cocaine self-administration dose-response curve." | 1.35 | Contribution of ventral tegmental GABA receptors to cocaine self-administration in rats. ( Backes, EN; Hemby, SE, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Backes, EN | 1 |
| Hemby, SE | 1 |
1 other study available for 2-hydroxysaclofen and Cocaine-Related Disorders
| Article | Year |
|---|---|
Contribution of ventral tegmental GABA receptors to cocaine self-administration in rats.
Topics: Animals; Baclofen; Cocaine-Related Disorders; Conditioning, Operant; Dose-Response Relationship, Dru | 2008 |