2-hydroxyestradiol has been researched along with Adenoma* in 1 studies
1 other study(ies) available for 2-hydroxyestradiol and Adenoma
| Article | Year |
|---|---|
Failure of 2 Hydroxyestradiol to interact with dopamine inhibition of human prolactin secretion in vitro and with dopamine receptors of prolactin-secreting adenomas.
The ability of 2-Hydroxyestradiol, a catecholestrogen, and 17 beta Estradiol to interact with the dopamine inhibition of prolactin and with dopamine receptors has been tested on dispersed human prolactin-secreting cells obtained from ten pituitary adenomas. There is a 80% inhibition of prolactin secretion obtained by addition of dopamine in a superfusion system. This inhibition is not affected by preexposure to the steroids, or by their introduction into the perifusion medium. Moreover 2 Hydroxyestradiol and 17 beta Estradiol do not interact with the binding of 3H Domperidone to DA receptors. Topics: Adenoma; Binding, Competitive; Dopamine Antagonists; Estradiol; Humans; In Vitro Techniques; Prolactin; Receptors, Dopamine | 1983 |