Page last updated: 2024-09-03

2-hydroxydesipramine and Depressive Disorder

2-hydroxydesipramine has been researched along with Depressive Disorder in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199012 (57.14)18.7374
1990's8 (38.10)18.2507
2000's1 (4.76)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bock, J; Bowers, MB; Jatlow, PI; Nelson, JC; Quinlan, DM1
Cooke, RG; Persad, E; Reed, KL; Stancer, HC; Warsh, JJ1
Jatlow, PI; Nelson, JC; Price, LH1
Bock, JL; Jatlow, PI; Nelson, JC1
Miescke, KJ; Musa, MN1
Baldessarini, RJ; Biederman, J; Flood, JG; Puopolo, PR; Wilens, TE2
Cooper, TB; Johnson, MH; Nelson, LD; Stern, SL; Suckow, RF1
Hirokane, G; Morita, S; Shimoda, K; Someya, T; Takahashi, S; Yokono, A1
Baldessarini, RJ; Biederman, J; Flood, JG; McDermott, SP; Puopolo, PR; Wilens, TE1
Barnhill, JG1
Cooper, TB; Roose, SP; Suckow, RF1
Cooper, TB; Johnson, MH; Nelson, LD; Ribner, HS; Stern, SL; Suckow, RF1
Bupp, SJ; Preskorn, SH; Weller, EB; Weller, RA1
Atillasoy, E; Jatlow, PI; Mazure, C; Nelson, JC1
Jatlow, PI; Mazure, C; Nelson, JC1
Jatlow, PI; Nelson, JC1
Dubbin, JD; Kutcher, SP; Reid, K; Shulman, KI1
Reed, KL; Stancer, HC1
Kutcher, SP; Reed, K; Shulman, KI1
Amsterdam, JD; Brunswick, DJ; Potter, L; Rickels, K; Winokur, A1

Trials

1 trial(s) available for 2-hydroxydesipramine and Depressive Disorder

ArticleYear
2-Hydroxydesipramine and desipramine plasma levels and electrocardiographic effects in depressed younger adults.
    Journal of clinical psychopharmacology, 1991, Volume: 11, Issue:2

    Topics: Adult; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Depressive Disorder; Desipramine; Electrocardiography; Female; Heart Block; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Risk Factors; Single-Blind Method

1991

Other Studies

20 other study(ies) available for 2-hydroxydesipramine and Depressive Disorder

ArticleYear
Major adverse reactions during desipramine treatment: relationship to plasma drug concentrations, concomitant antipsychotic treatment, and patient characteristics.
    Archives of general psychiatry, 1982, Volume: 39, Issue:9

    Topics: Adult; Age Factors; Aged; Antipsychotic Agents; Constipation; Delirium; Depressive Disorder; Desipramine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypotension, Orthostatic; Male; Middle Aged; Mood Disorders; Urination Disorders

1982
The nonlinear kinetics of desipramine and 2-hydroxydesipramine in plasma.
    Clinical pharmacology and therapeutics, 1984, Volume: 36, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Amitriptyline; Chromatography, High Pressure Liquid; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Male; Middle Aged; Nortriptyline; Random Allocation

1984
Effects of desipramine on clinical liver function tests.
    The American journal of psychiatry, 1984, Volume: 141, Issue:6

    Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Liver; Liver Function Tests; Male; Middle Aged

1984
Clinical implications of 2-hydroxydesipramine plasma concentrations.
    Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:2

    Topics: Depressive Disorder; Desipramine; Drug Evaluation; Humans; Middle Aged; Regression Analysis

1983
Pharmacogenetics of desipramine metabolism.
    International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:3

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Depressive Disorder; Desipramine; Energy Metabolism; Female; Genotype; Humans; Male; Mathematics; Middle Aged; Pharmacogenetics; Statistics as Topic

1994
Electrocardiographic effects of desipramine and 2-hydroxydesipramine in children, adolescents, and adults treated with desipramine.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1993, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Child; Depressive Disorder; Desipramine; Electrocardiography; Female; Heart Rate; Humans; Male; Metabolic Clearance Rate; Risk Factors

1993
2-Hydroxydesipramine and desipramine plasma levels: how are they related to antidepressant response?
    International clinical psychopharmacology, 1996, Volume: 11, Issue:4

    Topics: Adult; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales

1996
Metabolism of desipramine in Japanese psychiatric patients: the impact of CYP2D6 genotype on the hydroxylation of desipramine.
    Pharmacology & toxicology, 2000, Volume: 86, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Tricyclic; Asian People; Cytochrome P-450 CYP2D6; Depressive Disorder; Desipramine; Female; Genotype; Humans; Hydroxylation; Japan; Male; Middle Aged

2000
Fluoxetine inhibits desipramine metabolism.
    Archives of general psychiatry, 1992, Volume: 49, Issue:9

    Topics: Attention Deficit Disorder with Hyperactivity; Depressive Disorder; Desipramine; Drug Interactions; Drug Therapy, Combination; Fluoxetine; Humans; Retrospective Studies

1992
Plasma desipramine levels and ECG changes in depressed young adults.
    Journal of clinical psychopharmacology, 1992, Volume: 12, Issue:2

    Topics: Adult; Alcoholism; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged

1992
Developmental changes in serum concentrations of desipramine and 2-hydroxydesipramine during treatment with desipramine.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1992, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged

1992
Effect of fluoxetine on plasma desipramine and 2-hydroxydesipramine.
    Biological psychiatry, 1992, Jan-15, Volume: 31, Issue:2

    Topics: Aged; Depressive Disorder; Desipramine; Drug Therapy, Combination; Female; Fluoxetine; Humans

1992
Plasma levels of imipramine and metabolites in 68 hospitalized children.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1989, Volume: 28, Issue:3

    Topics: Adolescent; Child; Depressive Disorder; Desipramine; Female; Humans; Imipramine; Male; Psychiatric Department, Hospital

1989
Hydroxydesipramine in the elderly.
    Journal of clinical psychopharmacology, 1988, Volume: 8, Issue:6

    Topics: Administration, Oral; Aged; Aged, 80 and over; Depressive Disorder; Desipramine; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged

1988
Antidepressant activity of 2-hydroxydesipramine.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:3

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Prospective Studies; Time Factors

1988
Nonlinear desipramine kinetics: prevalence and importance.
    Clinical pharmacology and therapeutics, 1987, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Depressive Disorder; Desipramine; Dose-Response Relationship, Drug; Female; Humans; Kinetics; Male; Middle Aged

1987
Electrocardiogram changes and therapeutic desipramine and 2-hydroxy-desipramine concentrations in elderly depressives.
    The British journal of psychiatry : the journal of mental science, 1986, Volume: 148

    Topics: Aged; Depressive Disorder; Desipramine; Electrocardiography; Female; Humans; Male; Middle Aged; Time Factors

1986
Desipramine and 2-hydroxydesipramine in human breast milk and the nursing infant's serum.
    The American journal of psychiatry, 1986, Volume: 143, Issue:12

    Topics: Adult; Breast Feeding; Depressive Disorder; Desipramine; Female; Humans; Infant, Newborn; Kinetics; Milk, Human

1986
Desipramine plasma concentration and therapeutic response in elderly depressives: a naturalistic pilot study.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1986, Volume: 31, Issue:8

    Topics: Aged; Aged, 80 and over; Depressive Disorder; Desipramine; Dexamethasone; Female; Humans; Hydrocortisone; Male; Middle Aged

1986
Desipramine and 2-hydroxydesipramine plasma levels in endogenous depressed patients. Lack of correlation with therapeutic response.
    Archives of general psychiatry, 1985, Volume: 42, Issue:4

    Topics: Adolescent; Adult; Depressive Disorder; Desipramine; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales

1985