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2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione and Depressive Disorder

2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione has been researched along with Depressive Disorder in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's9 (64.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bahro, M; Berger, M; Gann, H; Hohagen, F; Lis, S; Riemann, D; Stadmüller, G1
Bahro, M; Berger, M; Hohagen, F; Riemann, D1
Holsboer, F; Krieg, JC; Krumrey, K; Lauer, CJ; Schreiber, W1
Berger, M; Dressing, H; Gann, H; Hohagen, F; Müller, WE; Riemann, D1
Berger, M; Riemann, D1
Berger, M; Krieg, C; Riemann, D1
Berger, M; Fleckenstein, P; Gann, H; Hohagen, F; Olbrich, R; Riemann, D1
Berger, M; Krieg, JC; Lauer, CJ; Riemann, D; Zulley, J1
Goetz, R; Walsh, BT1
Berger, M; Krieg, JC; Lauer, C; Riemann, D; Zulley, J2
Berger, M; Höchli, D; Riemann, D; Spiegel, R1
Berger, M; Höchli, D; Lauer, C; von Zerssen, D; Zulley, J1
Berger, M; Krieg, JC1

Trials

7 trial(s) available for 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione and Depressive Disorder

ArticleYear
Cholinergic neurotransmission, REM sleep and depression.
    Journal of psychosomatic research, 1994, Volume: 38 Suppl 1

    Topics: Adolescent; Adult; Aged; Alzheimer Disease; Brain Stem; Cholinergic Agonists; Cholinergic Fibers; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Galantamine; Humans; Male; Mental Disorders; Middle Aged; Parasympathomimetics; Physostigmine; Polysomnography; Reaction Time; Receptors, Muscarinic; Sleep Stages; Sleep Wake Disorders; Sleep, REM; Succinimides; Synaptic Transmission; Tacrine

1994
The sleep structure of patients with anxiety disorders in comparison to that of healthy controls and depressive patients under baseline conditions and after cholinergic stimulation.
    Journal of affective disorders, 1992, Volume: 26, Issue:3

    Topics: Adult; Anxiety Disorders; Arousal; Brain Stem; Cerebral Cortex; Cholinergic Fibers; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Panic Disorder; Parasympathomimetics; Polysomnography; Reaction Time; Sleep Stages; Sleep, REM; Succinimides

1992
Sleep, age, depression and the cholinergic REM induction test with RS 86.
    Progress in neuro-psychopharmacology & biological psychiatry, 1992, Volume: 16, Issue:3

    Topics: Adult; Aging; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Parasympathomimetics; Sleep; Sleep, REM; Succinimides

1992
Cholinergic drugs as diagnostic and therapeutic tools in affective disorders.
    Acta psychiatrica Scandinavica. Supplementum, 1991, Volume: 366

    Topics: Adult; Bipolar Disorder; Brain; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Parasympathomimetics; Pituitary-Adrenal System; Reaction Time; Receptors, Cholinergic; Sleep, REM; Succinimides

1991
A polysomnographic study in young psychiatric inpatients: major depression, anorexia nervosa, bulimia nervosa.
    Journal of affective disorders, 1990, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Anorexia Nervosa; Bulimia; Depressive Disorder; Electroencephalography; Evoked Potentials; Female; Humans; Male; Parasympathomimetics; Randomized Controlled Trials as Topic; Reaction Time; Sleep Stages; Sleep, REM; Succinimides

1990
[Sleep in anorexia nervosa, bulimia nervosa and depressive diseases: a polysomnographic comparative study].
    Fortschritte der Neurologie-Psychiatrie, 1989, Volume: 57, Issue:10

    Topics: Adult; Anorexia Nervosa; Bulimia; Depressive Disorder; Electroencephalography; Female; Humans; Male; Parasympathomimetics; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Reaction Time; Sleep Stages; Sleep, REM; Succinimides

1989
EEG sleep and the cholinergic REM induction test in anorexic and bulimic patients.
    Psychiatry research, 1988, Volume: 26, Issue:2

    Topics: Adult; Anorexia Nervosa; Bulimia; Cerebral Cortex; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Electroencephalography; Evoked Potentials; Female; Humans; Male; Random Allocation; Reaction Time; Sleep Stages; Sleep, REM; Succinimides

1988

Other Studies

7 other study(ies) available for 2-ethyl-8-methyl-2,8-diazaspiro(4,5)decane-1,3-dione and Depressive Disorder

ArticleYear
Sleep in depression: the influence of age, gender and diagnostic subtype on baseline sleep and the cholinergic REM induction test with RS 86.
    European archives of psychiatry and clinical neuroscience, 1994, Volume: 243, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Depressive Disorder; Female; Humans; Male; Middle Aged; Parasympathomimetics; Polysomnography; Psychiatric Status Rating Scales; Reaction Time; Receptors, Cholinergic; Receptors, Muscarinic; Sleep Stages; Sleep, REM; Succinimides; Wakefulness

1994
Cholinergic REM sleep induction test in subjects at high risk for psychiatric disorders.
    Biological psychiatry, 1992, Jul-01, Volume: 32, Issue:1

    Topics: Adult; Bipolar Disorder; Depressive Disorder; Female; Humans; Male; Parasympathomimetics; Polysomnography; Reaction Time; Receptors, Cholinergic; Risk Factors; Schizophrenia; Schizophrenic Psychology; Schizotypal Personality Disorder; Sleep, REM; Succinimides

1992
Effect of RS 86 on REM latency in schizophrenia.
    Psychiatry research, 1991, Volume: 38, Issue:1

    Topics: Adult; Depressive Disorder; Electroencephalography; Female; Humans; Male; Parasympathomimetics; Reaction Time; Receptors, Cholinergic; Schizophrenia; Schizophrenic Psychology; Sleep, REM; Succinimides

1991
Sleep architecture in eating disorders.
    Archives of general psychiatry, 1990, Volume: 47, Issue:9

    Topics: Anorexia Nervosa; Bulimia; Depressive Disorder; Electroencephalography; Feeding and Eating Disorders; Humans; Parasympathomimetics; Sleep Wake Disorders; Sleep, REM; Succinimides

1990
The cholinergic rapid eye movement sleep induction test with RS-86. State or trait marker of depression?
    Archives of general psychiatry, 1989, Volume: 46, Issue:5

    Topics: Adolescent; Adult; Depressive Disorder; Diagnosis, Differential; Female; Half-Life; Humans; Male; Mental Disorders; Middle Aged; Personality Inventory; Receptors, Cholinergic; Sleep; Sleep, REM; Succinimides

1989
Cholinomimetic drug RS 86, REM sleep, and depression.
    Lancet (London, England), 1985, Jun-15, Volume: 1, Issue:8442

    Topics: Administration, Oral; Adolescent; Adult; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Parasympathomimetics; Sleep, REM; Succinimides

1985
REM sleep and cortisol response to the cholinergic challenge with RS 86 in normals and depressives.
    Acta psychiatrica Scandinavica, 1987, Volume: 76, Issue:5

    Topics: Adult; Depressive Disorder; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Middle Aged; Pituitary-Adrenal System; Receptors, Muscarinic; Sleep, REM; Succinimides

1987