Compounds > 2-deoxyribose-1-phosphate--(alpha-d-erythro)-isomer

2-deoxyribose-1-phosphate--(alpha-d-erythro)-isomer and Adenocarcinoma

2-deoxyribose-1-phosphate--(alpha-d-erythro)-isomer has been researched along with Adenocarcinoma* in 1 studies

Other Studies

1 other study(ies) available for 2-deoxyribose-1-phosphate--(alpha-d-erythro)-isomer and Adenocarcinoma

Article	Year
Metabolism of 5-fluorouracil in various human normal and tumor tissues. Gan, 1981, Volume: 72, Issue:6 The metabolism of 5-fluorouracil (5-FU) in tumors and normal tissues of humans was investigated in vitro. Phosphorylation of 5-FU was faster in tumor tissues than in normal tissues. Phosphorylating activity with 2-deoxy-alpha-D-ribose 1-phosphate (dRiblP) and ATP as cofactors was more active than that with alpha D-ribose 1-phosphate (RiblP) and ATP, or 5-phospho-alpha-D-ribosyldiphosphate (PPRibP) as cofactors. Phosphorylating activity in squamous cell carcinoma of the lung was similar to that in adenocarcinomas. Degradation of 5-FU was much faster in the liver than in other tissues including tumor tissues. Topics: Adenocarcinoma; Adenosine Triphosphate; Carcinoma, Squamous Cell; Digestive System; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver; Lung; Lung Neoplasms; Neoplasms; Phosphoribosyl Pyrophosphate; Phosphorylation; Ribosemonophosphates	1981

Article

Year

Metabolism of 5-fluorouracil in various human normal and tumor tissues.

Gan, 1981, Volume: 72, Issue:6

The metabolism of 5-fluorouracil (5-FU) in tumors and normal tissues of humans was investigated in vitro. Phosphorylation of 5-FU was faster in tumor tissues than in normal tissues. Phosphorylating activity with 2-deoxy-alpha-D-ribose 1-phosphate (dRiblP) and ATP as cofactors was more active than that with alpha D-ribose 1-phosphate (RiblP) and ATP, or 5-phospho-alpha-D-ribosyldiphosphate (PPRibP) as cofactors. Phosphorylating activity in squamous cell carcinoma of the lung was similar to that in adenocarcinomas. Degradation of 5-FU was much faster in the liver than in other tissues including tumor tissues.

Topics: Adenocarcinoma; Adenosine Triphosphate; Carcinoma, Squamous Cell; Digestive System; Fluorouracil; Gastrointestinal Neoplasms; Humans; Liver; Lung; Lung Neoplasms; Neoplasms; Phosphoribosyl Pyrophosphate; Phosphorylation; Ribosemonophosphates

1981