2-chloropropionic acid has been researched along with Necrosis in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (76.92) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lock, EA; Simpson, MG; Widdowson, PS; Wyatt, I | 1 |
| Gyte, A; Lock, EA; Simpson, M; Widdowson, P; Wyatt, I | 1 |
| Dunn, D; Farnworth, M; Gyte, A; Lock, EA; Moore, RB; Simpson, MG; Widdowson, PS; Wyatt, I | 1 |
| Gyte, AJ; Jones, HB; Lock, EA; Simpson, MG; Widdowson, PS; Wyatt, I | 1 |
| Gyte, A; Lock, EA; Simpson, MG; Widdowson, PS; Wyatt, I | 1 |
| Gyte, AJ; Upton, R; Widdowson, PS; Wyatt, I | 1 |
| Gyte, A; Lock, EA; Mainwaring, G; Widdowson, PS; Wyatt, I | 1 |
| Coutts, CT; Foster, J; Gyte, A; Upton, R; Widdowson, PS; Wyatt, I | 1 |
| Duffell, SJ; Gyte, A; Lock, EA; Simpson, MG; Wyatt, I | 1 |
| Gyte, A; Moores, R; Pitts, M; Smith, JC; Upton, R; Widdowson, PS; Wyatt, I | 1 |
| Duffell, S; Gyte, A; Lock, EA; Wyatt, I | 2 |
| Bachelard, HS; Checkley, D; Lock, EA; Prior, M; Waterton, JC; Williams, RE | 1 |
13 other study(ies) available for 2-chloropropionic acid and Necrosis
| Article | Year |
|---|---|
[125I]endothelin binding in rat cerebellum is increased following L-2-chloropropionic-acid-induced granule cell necrosis.
Topics: Animals; Autoradiography; Brain; Cerebellum; Endothelins; Hydrocarbons, Chlorinated; Iodine Radioisotopes; Male; Necrosis; Neurotoxins; Propionates; Rats; Rats, Inbred Strains; Receptors, Endothelin; Reference Values; Time Factors | 1995 |
Chloropropionic acid-induced alterations in glucose metabolic status: possible relevance to cerebellar granule cell necrosis.
Topics: Animals; Blood Glucose; Cerebellum; Cytoplasmic Granules; Glucose; Hydrocarbons, Chlorinated; Lactates; Lactic Acid; Male; Necrosis; Propionates; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1995 |
Possible role of nitric oxide in the development of L-2-chloropropionic acid-induced cerebellar granule cell necrosis.
Topics: Animals; Aspartic Acid; Cerebellum; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Hydrocarbons, Chlorinated; In Vitro Techniques; Indazoles; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Ornithine; Propionates; Rats | 1996 |
Neuropathological changes in rat brain following oral administration of 2-chloropropionic acid.
Topics: Administration, Oral; Animals; Body Water; Brain; Brain Chemistry; Cerebellum; Hydrocarbons, Chlorinated; Male; Necrosis; Propionates; Rats; Stereoisomerism; Time Factors | 1996 |
The role of glutathione in L-2-chloropropionic acid induced cerebellar granule cell necrosis in the rat.
Topics: Administration, Oral; Animals; Buthionine Sulfoximine; Cerebellar Cortex; Cerebellum; Cytoplasmic Granules; Drug Synergism; Glutathione; Hydrocarbons, Chlorinated; Male; Necrosis; Neurons; Propionates; Rats; Rats, Inbred Strains | 1996 |
Failure of glycine site NMDA receptor antagonists to protect against L-2-chloropropionic acid-induced neurotoxicity highlights the uniqueness of cerebellar NMDA receptors.
Topics: Administration, Oral; Animals; Cell Death; Cerebellum; Excitatory Amino Acid Antagonists; Hydrocarbons, Chlorinated; Male; Models, Biological; Necrosis; Neurons; Neuroprotective Agents; Neurotoxins; Propionates; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Treatment Outcome | 1996 |
Glutathione depletion in the liver and brain produced by 2-chloropropionic acid: relevance to cerebellar granule cell necrosis.
Topics: Animals; Brain; Cerebellum; Cytoplasmic Granules; Glutathione; Hydrocarbons, Chlorinated; Kidney; Liver; Male; Necrosis; Propionates; Rats; Rats, Wistar | 1996 |
Calpain activation and not oxidative damage mediates L-2-chloropropionic acid-induced cerebellar granule cell necrosis.
Topics: Administration, Oral; Animals; Antioxidants; Ascorbic Acid; Aspartic Acid; Blotting, Western; Calpain; Cerebellum; Free Radicals; Glutamic Acid; Hydrocarbons, Chlorinated; Lipid Peroxidation; Male; Necrosis; Nervous System Diseases; Neurons; Oxidative Stress; Propionates; Rats; Spectrin | 1997 |
Neuroprotection afforded by MK-801 against L-2-chloropropionic acid-induced cerebellar granule cell necrosis in the rat.
Topics: Amino Acids; Animals; Body Water; Body Weight; Cerebellum; Dizocilpine Maleate; Hydrocarbons, Chlorinated; Male; Necrosis; Neurotoxins; Propionates; Rats; Sodium | 1997 |
L-2-chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists.
Topics: Animals; Aspartic Acid; Body Weight; Calcium Channel Blockers; Cerebellar Diseases; Cerebellum; Drug Synergism; Glycine; Hydrocarbons, Chlorinated; Male; Motor Activity; Necrosis; Nifedipine; Propionates; Rats; Sodium; Verapamil | 1997 |
The absence of cerebellar granule cell necrosis in the mouse following L-2-chloropropionic acid administration.
Topics: Animals; Blood Glucose; Cerebellum; Chromatography, High Pressure Liquid; Cytoplasmic Granules; Cytosol; Glutathione; Half-Life; Hydrocarbons, Chlorinated; Liver; Male; Mice; Necrosis; Propionates; Tissue Distribution | 2000 |
The effect of postnatal age on L-2-chloropropionic acid-induced cerebellar granule cell necrosis in the rat.
Topics: Age Factors; Animals; Cerebellum; Cytoplasmic Granules; Dose-Response Relationship, Drug; Forelimb; Habenula; Hindlimb; Hydrocarbons, Chlorinated; Male; Muscle Weakness; Necrosis; Propionates; Rats; Tissue Distribution; Weight Gain | 2001 |
MRI studies of the neurotoxic effects of L-2-chloropropionic acid on rat brain.
Topics: Animals; Brain Edema; Cell Survival; Cerebellum; Hydrocarbons, Chlorinated; Magnetic Resonance Imaging; Male; Necrosis; Neurons; Propionates; Rats; Rats, Inbred Strains; Spinocerebellar Degenerations | 2001 |