Compounds > 2-chloro-n(6)cyclopentyladenosine

Page last updated: 2024-09-03

2-chloro-n(6)cyclopentyladenosine and Heart Disease, Ischemic

2-chloro-n(6)cyclopentyladenosine has been researched along with Heart Disease, Ischemic in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	11 (61.11)	18.2507
2000's	7 (38.89)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baxter, GF; Hausenloy, DJ; Maddock, HL; Yellon, DM	1
Duchen, M; Hausenloy, D; Wynne, A; Yellon, D	1
Dobson, JG; Fenton, RA; Tikh, EI	1
Armstrong, S; Downey, JM; Ganote, CE	2
Camaioni, E; Casati, C; Conti, A; Cristalli, G; Dionisotti, S; Monopoli, A; Ongini, E	1
Baxter, GF; Marber, MS; Patel, VC; Yellon, DM	1
Downey, JM; Olsson, RA; Thompson, R; Tsuchida, A	1
Downey, JM; Liu, Y	1
Downey, JM; Liu, GS; Tsuchida, A; Wilborn, WH	1
Baxter, GF; Kerac, M; Yellon, DM; Zaman, MJ	1
Jacobson, KA; Jiang, JL; Liang, BT; Stambaugh, K	1
de Jong, JW; de Jonge, R	2
Brodmann, M; Lueger, A; Stark, G; Stark, U	1
Balas, N; Jacobson, KA; Nawrath, H; Safran, N; Shainberg, A; Shneyvays, V	1
Latchman, DS; Schulman, D; Yellon, DM	1
Ashraf, M; Ayub, A; Kudo, M; Wang, Y; Xu, M	1

Reviews

1 review(s) available for 2-chloro-n(6)cyclopentyladenosine and Heart Disease, Ischemic

Article	Year
Ischemic preconditioning--do we need more (pharmacological) experiments? Basic research in cardiology, 1997, Volume: 92 Suppl 2 Topics: Adenosine; Animals; Blood Flow Velocity; Bradykinin; Coronary Vessels; Humans; Ischemic Preconditioning, Myocardial; Myocardial Ischemia; Norepinephrine; Purinergic P1 Receptor Agonists	1997

Other Studies

17 other study(ies) available for 2-chloro-n(6)cyclopentyladenosine and Heart Disease, Ischemic

Article	Year
Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning? Cardiovascular research, 2002, Aug-15, Volume: 55, Issue:3 Topics: Adenosine; Analysis of Variance; Animals; Atractyloside; Calcineurin Inhibitors; Cyclosporine; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Hydroxy Acids; Ion Channels; Ischemic Preconditioning, Myocardial; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Ischemia; Myocardial Reperfusion Injury; Perfusion; Permeability; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Purinergic P1 Receptor Agonists; Random Allocation; Rats; Rats, Sprague-Dawley; Tacrolimus	2002
Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection. Circulation, 2004, Apr-13, Volume: 109, Issue:14 Topics: 2,4-Dinitrophenol; Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Cardiotonic Agents; Cells, Cultured; Cyclosporine; Diazoxide; Electric Conductivity; Ion Channel Gating; Ion Channels; Ion Transport; Ischemic Preconditioning, Myocardial; Lactones; Macromolecular Substances; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Phosphorylation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Spiro Compounds; Uncoupling Agents; Vasodilator Agents	2004
Contractile effects of adenosine A1 and A2A receptors in isolated murine hearts. American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:1 Topics: Adenosine; Animals; Heart; Isoproterenol; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Ischemia; Phenethylamines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Xanthines	2006
Preconditioning of isolated rabbit cardiomyocytes: induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor. Cardiovascular research, 1994, Volume: 28, Issue:1 Topics: Adenosine; Animals; Cell Size; Cell Survival; Cells, Cultured; Glucose; Heart; Myocardial Ischemia; Myocardium; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rabbits; Theophylline; Time Factors	1994
Pharmacology of the highly selective A1 adenosine receptor agonist 2-chloro-N6-cyclopentyladenosine. Arzneimittel-Forschung, 1994, Volume: 44, Issue:12 Topics: Adenosine; Anesthesia; Animals; Behavior, Animal; Cattle; Coronary Circulation; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Mice; Myocardial Contraction; Myocardial Ischemia; Platelet Aggregation; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Xanthines	1994
Adenosine receptor involvement in a delayed phase of myocardial protection 24 hours after ischemic preconditioning. Circulation, 1994, Volume: 90, Issue:6 Topics: Adenosine; Animals; Heart; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Rabbits; Receptors, Purinergic P1; Theophylline; Time Factors	1994
The anti-infarct effect of an adenosine A1-selective agonist is diminished after prolonged infusion as is the cardioprotective effect of ischaemic preconditioning in rabbit heart. Journal of molecular and cellular cardiology, 1994, Volume: 26, Issue:3 Topics: Acetylcholine; Adenosine; Animals; Bradycardia; Drug Tolerance; Female; Hemodynamics; Hypotension; Infusions, Intravenous; Male; Muscle Proteins; Myocardial Infarction; Myocardial Ischemia; Myocardium; Necrosis; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Muscarinic; Receptors, Purinergic P1	1994
Adenosine and A1 selective agonists offer minimal protection against ischaemic injury to isolated rat cardiomyocytes. Cardiovascular research, 1993, Volume: 27, Issue:9 Topics: Adenosine; Animals; Carbachol; Cell Death; Cells, Cultured; Iodoacetates; Iodoacetic Acid; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Rats; Rats, Sprague-Dawley; Theophylline	1993
Preconditioning against infarction in the rat heart does not involve a pertussis toxin sensitive G protein. Cardiovascular research, 1993, Volume: 27, Issue:4 Topics: Acetylcholine; Adenosine; Animals; Arrhythmias, Cardiac; GTP-Binding Proteins; Heart Rate; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Virulence Factors, Bordetella	1993
Pretreatment with the adenosine A1 selective agonist, 2-chloro-N6-cyclopentyladenosine (CCPA), causes a sustained limitation of infarct size in rabbits. Cardiovascular research, 1993, Volume: 27, Issue:4 Topics: Adenosine; Animals; Disease Models, Animal; Female; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Rabbits; Receptors, Purinergic	1993
Protection against global ischemia in the rabbit isolated heart 24 hours after transient adenosine A1 receptor activation. Cardiovascular drugs and therapy, 1997, Volume: 11, Issue:1 Topics: Adenosine; Animals; Blood Pressure; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline	1997
A novel cardioprotective function of adenosine A1 and A3 receptors during prolonged simulated ischemia. The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 2 Topics: Adenosine; Animals; Cardiotonic Agents; Cell Hypoxia; Cells, Cultured; Chick Embryo; Dihydropyridines; Heart; Heart Ventricles; Myocardial Ischemia; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Xanthines	1997
Ischemic preconditioning and glucose metabolism during low-flow ischemia: role of the adenosine A1 receptor. Cardiovascular research, 1999, Volume: 43, Issue:4 Topics: Adenosine; Animals; Glucose; Glycolysis; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Myocardium; Perfusion; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Regional Blood Flow; Theophylline	1999
Antiarrhythmic effects of adenosine on ischemia-induced ventricular fibrillation. Journal of critical care, 2001, Volume: 16, Issue:1 Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Dipyridamole; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Ischemia; Purinergic P1 Receptor Agonists; Theophylline; Ventricular Fibrillation	2001
Cardioprotective effects of adenosine A1 and A3 receptor activation during hypoxia in isolated rat cardiac myocytes. Molecular and cellular biochemistry, 2001, Volume: 217, Issue:1-2 Topics: Adenosine; Animals; Animals, Newborn; Cell Hypoxia; Cells, Cultured; L-Lactate Dehydrogenase; Microscopy, Electron; Myocardial Ischemia; Myocardium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Pyridines; Rats; Receptor, Adenosine A3; Receptors, Purinergic P1; Xanthines	2001
Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:4 Topics: Adenosine; Aging; Animals; Diazoxide; Diglycerides; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Time Factors; Vasodilator Agents	2001
Adenosine A(1) receptor mediates late preconditioning via activation of PKC-delta signaling pathway. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:1 Topics: Acetophenones; Adenosine; Animals; Benzopyrans; Creatine Kinase; Enzyme Inhibitors; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Isoenzymes; Male; Mice; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Kinase C; Protein Kinase C-delta; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Signal Transduction; Ventricular Function, Left	2002