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2-chloro-n(6)cyclopentyladenosine and Disease Models, Animal

2-chloro-n(6)cyclopentyladenosine has been researched along with Disease Models, Animal in 19 studies

*Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. [MeSH]

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.26)18.2507
2000's9 (47.37)29.6817
2010's6 (31.58)24.3611
2020's3 (15.79)2.80

Authors

AuthorsStudies
Batra, VK; Borron, P; Mustafa, SJ; Nadeem, A; Obiefuna, PC; Wilson, CN1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Langston, JL; Meads, KL; Myers, TM; Shih, TM; Thomas, TP1
Acon-Chen, C; Loughery, TN; Shih, TM; Whitten, KA1
Fukuda, M; Hino, H; Ishii, E; Kuzume, K; Morimoto, T; Suzuki, Y1
Guo, CX; Gupta, R; Housley, GD; Thorne, PR; Vlajkovic, SM; Wong, AC1
Mustafa, SJ; Nadeem, A; Ponnoth, DS; Tilley, S1
Antonioli, L; Awwad, O; Blandizzi, C; Colucci, R; Del Tacca, M; Fornai, M; Ghisu, N; Tuccori, M1
Cock, HR; Hamil, NE; Walker, MC1
Chen, S; Dong, H; Hou, L; Hu, S; Wang, S; Xiong, L; Zhang, H; Zhang, J1
Boison, D; Güttinger, M; Huber, A; Möhler, H1
Boison, D; Fritschy, JM; Gouder, N1
Cristalli, G; Morelli, M; Pinna, A; Volpini, R1
Bardenheuer, HJ; Heller, AR; Koch, T; Plaschke, K; Rothermel, J; Schmeck, J; Weigand, MA; Wendel, M1
Jacobson, KA; Liang, BT; Wang, R; Wu, D; Zambraski, E; Zheng, J1
Ajamieh, HH; Berlanga, J; Carmona, AM; León Fernández, OS; Menéndez, S; Re, L; Viebahn-Hánsler, R1
Carneiro, FS; Carneiro, ZN; Giachini, FRC; Inscho, EW; Leite, R; Lima, VV; Tostes, RC; Webb, RC1
Downey, JM; Liu, GS; Tsuchida, A; Wilborn, WH1
Chung, ES; Dobson, JG; Fenton, RA; Lorbar, M; Meyer, TE; Norton, GR; Perlini, S; Woodiwiss, AJ1

Other Studies

19 other study(ies) available for 2-chloro-n(6)cyclopentyladenosine and Disease Models, Animal

ArticleYear
A novel A1 adenosine receptor antagonist, L-97-1 [3-[2-(4-aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], reduces allergic responses to house dust mite in an allergic rabbit model of asthma.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Anti-Asthmatic Agents; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Dose-Response Relationship, Drug; Dust; Histamine; Mites; Phosphodiesterase Inhibitors; Purines; Rabbits; Radioligand Assay; Receptor, Adenosine A1

2005
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Evaluation of adenosine A1 receptor agonists as neuroprotective countermeasures against Soman intoxication in rats.
    Toxicology and applied pharmacology, 2021, 04-01, Volume: 416

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Anticonvulsants; Behavior, Animal; Brain; Deoxyadenosines; Disease Models, Animal; Male; Neuroprotective Agents; Organophosphate Poisoning; Rats, Sprague-Dawley; Receptor, Adenosine A1; Seizures; Soman

2021
Intramuscularly administered A1 adenosine receptor agonists as delayed treatment for organophosphorus nerve agent-induced Status Epilepticus.
    Toxicology and applied pharmacology, 2021, 05-15, Volume: 419

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Anticonvulsants; Brain; Deoxyadenosines; Disease Models, Animal; Drug Administration Schedule; Injections, Intramuscular; Male; Neuroprotective Agents; Norbornanes; Rats, Sprague-Dawley; Sarin; Soman; Status Epilepticus; Time Factors

2021
Adenosine A1 receptor blockage mediates theophylline-associated seizures.
    Epilepsia, 2010, Volume: 51, Issue:3

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Kinase; Animals; Behavior, Animal; Body Temperature; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Enzyme Inhibitors; Hyperthermia, Induced; Injections, Intraperitoneal; Male; Rats; Rats, Inbred Lew; Seizures; Theophylline; Tubercidin

2010
Post exposure administration of A(1) adenosine receptor agonists attenuates noise-induced hearing loss.
    Hearing research, 2010, Volume: 260, Issue:1-2

    Topics: Acoustic Stimulation; Adenosine; Adenosine A1 Receptor Agonists; Animals; Auditory Threshold; Cochlea; Cochlear Microphonic Potentials; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Hearing Loss, Noise-Induced; Male; Oxidative Stress; Phenethylamines; Rats; Rats, Wistar; Receptor, Adenosine A1; Time Factors; Tyrosine

2010
Involvement of A1 adenosine receptors in altered vascular responses and inflammation in an allergic mouse model of asthma.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:1

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Administration, Inhalation; Aerosols; Ambrosia; Animals; Antigens, Plant; Aorta; Asthma; Blotting, Western; Bronchial Hyperreactivity; Bronchoconstriction; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-5; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Plethysmography, Whole Body; Polymerase Chain Reaction; Receptor, Adenosine A1; RNA, Messenger; Vasodilation

2010
Differential recruitment of high affinity A1 and A2A adenosine receptors in the control of colonic neuromuscular function in experimental colitis.
    European journal of pharmacology, 2011, Jan-15, Volume: 650, Issue:2-3

    Topics: 5'-Nucleotidase; Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Benzenesulfonates; Colitis; Colon; Disease Models, Animal; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Xanthines

2011
Acute down-regulation of adenosine A(1) receptor activity in status epilepticus.
    Epilepsia, 2012, Volume: 53, Issue:1

    Topics: Adenosine; Animals; Disease Models, Animal; Down-Regulation; Electric Stimulation; Electroencephalography; Hippocampus; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Status Epilepticus

2012
Noninvasive limb remote ischemic preconditioning contributes neuroprotective effects via activation of adenosine A1 receptor and redox status after transient focal cerebral ischemia in rats.
    Brain research, 2012, Jun-12, Volume: 1459

    Topics: Adenosine; Analysis of Variance; Animals; Brain Infarction; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Extremities; Glutathione; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Ischemic Preconditioning; Lipid Peroxidation; Male; Nervous System Diseases; Neuroprotective Agents; Nitrites; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Severity of Illness Index; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Xanthines

2012
Seizure suppression by adenosine A(2A) receptor activation in a rat model of audiogenic brainstem epilepsy.
    Neuroscience letters, 2002, Sep-06, Volume: 329, Issue:3

    Topics: Adenosine; Animals; Brain Stem; Disease Models, Animal; Dose-Response Relationship, Drug; Epilepsy, Reflex; Purinergic P1 Receptor Agonists; Rats; Rats, Mutant Strains; Receptor, Adenosine A2A

2002
Seizure suppression by adenosine A1 receptor activation in a mouse model of pharmacoresistant epilepsy.
    Epilepsia, 2003, Volume: 44, Issue:7

    Topics: Adenosine; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance; Electroencephalography; Epilepsy, Temporal Lobe; Hippocampus; Injections; Kainic Acid; Male; Mice; Mice, Inbred Strains; Purinergic P1 Receptor Agonists; Receptors, Purinergic P1; Temporal Lobe

2003
New adenosine A2A receptor antagonists: actions on Parkinson's disease models.
    European journal of pharmacology, 2005, Apr-11, Volume: 512, Issue:2-3

    Topics: Adenine; Adenosine; Adenosine A2 Receptor Antagonists; Animals; Antiparkinson Agents; Behavior, Animal; Binding, Competitive; Catalepsy; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Drug Synergism; Levodopa; Male; Molecular Structure; Parkinson Disease; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Tritium

2005
Adenosine A1 and A2 receptor agonists reduce endotoxin-induced cellular energy depletion and oedema formation in the lung.
    European journal of anaesthesiology, 2007, Volume: 24, Issue:3

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine Diphosphate; Adenosine Triphosphate; Analysis of Variance; Animals; Blood Pressure; Chromatography, High Pressure Liquid; Disease Models, Animal; Endotoxemia; Endotoxins; Energy Metabolism; Female; Lipopolysaccharides; Lung; Pulmonary Artery; Pulmonary Edema; Rabbits; Receptors, Purinergic P1; Respiratory Distress Syndrome; Time Factors; Uric Acid; Vasoconstriction

2007
Protective roles of adenosine A1, A2A, and A3 receptors in skeletal muscle ischemia and reperfusion injury.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:6

    Topics: Adenosine; Animals; Dihydropyridines; Disease Models, Animal; Hindlimb; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Phenethylamines; Phospholipase C beta; Pyrazoles; Pyrimidines; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptor, Adenosine A3; Reperfusion Injury; Signal Transduction; Xanthines

2007
Ozone oxidative preconditioning is mediated by A1 adenosine receptors in a rat model of liver ischemia/ reperfusion.
    Transplant international : official journal of the European Society for Organ Transplantation, 2008, Volume: 21, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Biomarkers; Disease Models, Animal; HSP72 Heat-Shock Proteins; Immunohistochemistry; Ischemic Preconditioning; Liver; Liver Transplantation; Male; NF-kappa B; Nitric Oxide; Oxidants, Photochemical; Oxidative Stress; Ozone; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Reperfusion Injury; Treatment Outcome; Tumor Necrosis Factor-alpha; Xanthines

2008
Adenosine actions are preserved in corpus cavernosum from obese and type II diabetic db/db mouse.
    The journal of sexual medicine, 2008, Volume: 5, Issue:5

    Topics: Acetylcholine; Adenosine; Adenosine Kinase; Animals; Diabetes Mellitus, Type 2; Dipyridamole; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Male; Mice; Mice, Mutant Strains; Mice, Obese; Muscle Contraction; Muscle, Smooth; Nitroprusside; Penis; Phenylephrine; Phosphodiesterase Inhibitors; Tubercidin; Vasoconstrictor Agents; Vasodilator Agents

2008
Pretreatment with the adenosine A1 selective agonist, 2-chloro-N6-cyclopentyladenosine (CCPA), causes a sustained limitation of infarct size in rabbits.
    Cardiovascular research, 1993, Volume: 27, Issue:4

    Topics: Adenosine; Animals; Disease Models, Animal; Female; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Rabbits; Receptors, Purinergic

1993
Antiadrenergic effects of adenosine in pressure overload hypertrophy.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:3

    Topics: Adenosine; Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Blood Pressure; Body Weight; Caffeine; Calcium; Cardiomegaly; Cells, Cultured; Coronary Circulation; Disease Models, Animal; Echocardiography; In Vitro Techniques; Inosine; Isoproterenol; Male; Myocardial Contraction; Myocardium; Organ Size; Perfusion; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley

2001