2-chloro-3--deoxyadenosine has been researched along with Neutropenia* in 1 studies
1 trial(s) available for 2-chloro-3--deoxyadenosine and Neutropenia
Article | Year |
---|---|
2-CdA in the treatment of hairy cell leukaemia.
Hairy cell leukaemia (HCL) is a rare lymphoproliferative disorder. Treatment options available are splenectomy, interferon, DCF and 2-CdA. 2-CdA is considered to have curative potential as proved by the other studies.. We gave 2-CdA in a dose of 0.09/kg/day as a continuous infusion in sixteen patients of hairy cell leukaemia.. Three patients developed neutropenia post transfusion. At the end of three months all patients were in remission. Two patients relapsed at the median follow-up of 15 months.. 2-CdA in HCL can achieve complete remission, prolonged survival and care as well. Topics: 2-Chloroadenosine; Adult; Antimetabolites, Antineoplastic; Deoxyadenosines; Female; Humans; Leukemia, Hairy Cell; Male; Middle Aged; Neutropenia; Survival Rate; Treatment Outcome | 2001 |