Compounds > 2-chloro-3-(4-methylanilino)naphthalene-1-4-dione

2-chloro-3-(4-methylanilino)naphthalene-1-4-dione and Trypanosomiasis--African

2-chloro-3-(4-methylanilino)naphthalene-1-4-dione has been researched along with Trypanosomiasis--African* in 1 studies

Other Studies

1 other study(ies) available for 2-chloro-3-(4-methylanilino)naphthalene-1-4-dione and Trypanosomiasis--African

Article	Year
Novel naphthoquinone derivatives: synthesis and activity against human African trypanosomiasis. Bioorganic & medicinal chemistry letters, 2013, Mar-01, Volume: 23, Issue:5 A series of naphthoquinone derivatives has been synthesized and tested for its biological activity against human African trypanosomiasis. The use of reverse micellar medium not only enhanced the conversion rate, but also showed selectivity towards mono-coupled product in aryl chloride-aniline coupling reactions. Two derivatives of naphthoquinone (9b and 9c) exhibited potent activity against Trypanosoma brucei in vitro with low cytotoxicity. Topics: Animals; Humans; Naphthoquinones; Structure-Activity Relationship; Trypanosomiasis, African	2013

Article

Year

Novel naphthoquinone derivatives: synthesis and activity against human African trypanosomiasis.

Bioorganic & medicinal chemistry letters, 2013, Mar-01, Volume: 23, Issue:5

A series of naphthoquinone derivatives has been synthesized and tested for its biological activity against human African trypanosomiasis. The use of reverse micellar medium not only enhanced the conversion rate, but also showed selectivity towards mono-coupled product in aryl chloride-aniline coupling reactions. Two derivatives of naphthoquinone (9b and 9c) exhibited potent activity against Trypanosoma brucei in vitro with low cytotoxicity.

Topics: Animals; Humans; Naphthoquinones; Structure-Activity Relationship; Trypanosomiasis, African

2013