2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane and Meningeal-Neoplasms

A 59-year-old man had developed within a few months walking disorders and rigidity of the left upper limb. I-FP-CIT SPECT/CT was performed in response to the suspicion of atypical parkinsonian syndrome. It showed an anomaly in presynaptic dopaminergic transmission on the right striatum and a voluminous expansive process on CT. MRI revealed an atypical meningioma. The patient had surgery for tumor removal. Later I-FP-CIT SPECT/CT showed normalization of presynaptic dopaminergic transmission on the right striatum.

Topics: Diagnostic Errors; Humans; Magnetic Resonance Imaging; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Neostriatum; Parkinsonian Disorders; Tomography, Emission-Computed, Single-Photon; Tropanes

A 76-year-old woman with about a 13-month history of bradykinesia, gait disturbance and resting tremor of right upper extremity was referred to Nuclear Medicine Department. A PET-CT with 229 MBq of F FP-CIT was performed to diagnose suspected early Parkinson's disease (PD). The PET-CT showed a mass lesion with highly intense focal dopamine transporter uptake in the right frontal lobe. A subsequent brain magnetic resonance image also showed a mass in the right frontal lobe demonstrating homogeneous enhancement and extensive surrounding edema, highly suggestive of a brain tumor.

Topics: Aged; Biological Transport; Female; Humans; Incidental Findings; Meningeal Neoplasms; Meningioma; Multimodal Imaging; Positron-Emission Tomography; Tomography, X-Ray Computed; Tropanes

Topics: Aged, 80 and over; Female; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Meningeal Neoplasms; Meningioma; Radionuclide Imaging; Radiopharmaceuticals; Tropanes