Compounds > 2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane

2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane and Hashimoto-Disease

2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane has been researched along with Hashimoto-Disease* in 2 studies

Other Studies

2 other study(ies) available for 2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane and Hashimoto-Disease

Article	Year
[A case of dementia with Lewy bodies and Hashimoto encephalopathy successfully treated with immunotherapy]. Rinsho shinkeigaku = Clinical neurology, 2019, Feb-23, Volume: 59, Issue:2 We report a 77-year-old woman suffering from dementia with Lewy bodies (DLB) who presented with Hashimoto encephalopathy. The patient began to mistakenly believe that another person was sleeping in her bed from approximately 70 years of age. She began to show symptoms of parkinsonism after 75 years of age. One night, the patient began to exhibit loitering behavior, and made incomprehensible comments while also exhibiting other abnormal behaviors. Clinical examination revealed rigidity and tremor of the limbs, as well as hallucination, abnormal speech and behavior. We first considered DLB. However, serum anti-thyroglobulin levels turned out to be elevated, indicating Hashimoto encephalopathy as well, and treated the patient with steroid pulse therapy. Her mental symptoms subsequently improved, but rigidity and tremor remained. Topics: Aged; Autoantibodies; Biomarkers; Encephalitis; Female; Hashimoto Disease; Humans; Immunotherapy; Iodine Radioisotopes; Lewy Body Disease; Methylprednisolone; Nortropanes; Phosphopyruvate Hydratase; Prednisolone; Pulse Therapy, Drug; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Treatment Outcome	2019
Improved 123I-Ioflupane Binding After Immunotherapy in Anti-NAE Antibody-Positive Hashimoto Encephalopathy That Clinically Mimicked Multiple System Atrophy. Clinical nuclear medicine, 2017, Volume: 42, Issue:8 We describe an 84-year-old man with anti-NH2-terminal of α-enolase antibody-positive Hashimoto encephalopathy that clinically mimicked multiple system atrophy who underwent investigation by dopamine transporter SPECT before and after immunotherapy. Before treatment, dopamine transporter SPECT showed reduced striatal I-ioflupane binding, with a mean specific binding ratio of 2.42, even though he had no apparent parkinsonism. After immunotherapy, mean specific binding ratio was improved to 3.22. Dopamine transporter SPECT was useful in this case to detect subclinical striatal dysfunction, and evaluation both before and after immunotherapy helped to distinguish between neurodegenerative disease and neuroimmunological disorder. Topics: Aged, 80 and over; Diagnosis, Differential; Dopamine Plasma Membrane Transport Proteins; Encephalitis; Hashimoto Disease; Humans; Immunotherapy; Male; Multiple System Atrophy; Nortropanes; Phosphopyruvate Hydratase; Tomography, Emission-Computed, Single-Photon	2017

Article

Year

[A case of dementia with Lewy bodies and Hashimoto encephalopathy successfully treated with immunotherapy].

Rinsho shinkeigaku = Clinical neurology, 2019, Feb-23, Volume: 59, Issue:2

We report a 77-year-old woman suffering from dementia with Lewy bodies (DLB) who presented with Hashimoto encephalopathy. The patient began to mistakenly believe that another person was sleeping in her bed from approximately 70 years of age. She began to show symptoms of parkinsonism after 75 years of age. One night, the patient began to exhibit loitering behavior, and made incomprehensible comments while also exhibiting other abnormal behaviors. Clinical examination revealed rigidity and tremor of the limbs, as well as hallucination, abnormal speech and behavior. We first considered DLB. However, serum anti-thyroglobulin levels turned out to be elevated, indicating Hashimoto encephalopathy as well, and treated the patient with steroid pulse therapy. Her mental symptoms subsequently improved, but rigidity and tremor remained.

Topics: Aged; Autoantibodies; Biomarkers; Encephalitis; Female; Hashimoto Disease; Humans; Immunotherapy; Iodine Radioisotopes; Lewy Body Disease; Methylprednisolone; Nortropanes; Phosphopyruvate Hydratase; Prednisolone; Pulse Therapy, Drug; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Treatment Outcome

2019

Improved 123I-Ioflupane Binding After Immunotherapy in Anti-NAE Antibody-Positive Hashimoto Encephalopathy That Clinically Mimicked Multiple System Atrophy.

Clinical nuclear medicine, 2017, Volume: 42, Issue:8

We describe an 84-year-old man with anti-NH2-terminal of α-enolase antibody-positive Hashimoto encephalopathy that clinically mimicked multiple system atrophy who underwent investigation by dopamine transporter SPECT before and after immunotherapy. Before treatment, dopamine transporter SPECT showed reduced striatal I-ioflupane binding, with a mean specific binding ratio of 2.42, even though he had no apparent parkinsonism. After immunotherapy, mean specific binding ratio was improved to 3.22. Dopamine transporter SPECT was useful in this case to detect subclinical striatal dysfunction, and evaluation both before and after immunotherapy helped to distinguish between neurodegenerative disease and neuroimmunological disorder.

Topics: Aged, 80 and over; Diagnosis, Differential; Dopamine Plasma Membrane Transport Proteins; Encephalitis; Hashimoto Disease; Humans; Immunotherapy; Male; Multiple System Atrophy; Nortropanes; Phosphopyruvate Hydratase; Tomography, Emission-Computed, Single-Photon

2017