2-aminothiazole has been researched along with Huntington Disease in 1 studies
2-aminothiazole: RN given refers to parent cpd; structure
1,3-thiazol-2-amine : A primary amino compound that is 1,3-thiazole substituted by an amino group at position 2.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leone, S | 1 |
| Mutti, C | 1 |
| Kazantsev, A | 1 |
| Sturlese, M | 1 |
| Moro, S | 1 |
| Cattaneo, E | 1 |
| Rigamonti, D | 1 |
| Contini, A | 1 |
1 other study available for 2-aminothiazole and Huntington Disease
| Article | Year |
|---|---|
SAR and QSAR study on 2-aminothiazole derivatives, modulators of transcriptional repression in Huntington's disease.
Topics: Gene Expression Regulation; Gene Library; Gene Silencing; Huntington Disease; Models, Molecular; Mol | 2008 |