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2-aminothiazole and Creutzfeldt-Jakob Syndrome

2-aminothiazole has been researched along with Creutzfeldt-Jakob Syndrome in 1 studies

2-aminothiazole: RN given refers to parent cpd; structure
1,3-thiazol-2-amine : A primary amino compound that is 1,3-thiazole substituted by an amino group at position 2.

Creutzfeldt-Jakob Syndrome: A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghaemmaghami, S1
Russo, M1
Renslo, AR1

Reviews

1 review available for 2-aminothiazole and Creutzfeldt-Jakob Syndrome

ArticleYear
Successes and challenges in phenotype-based lead discovery for prion diseases.
    Journal of medicinal chemistry, 2014, Aug-28, Volume: 57, Issue:16

    Topics: Animals; Brain; Creutzfeldt-Jakob Syndrome; Disease Models, Animal; Drug Discovery; Drug Evaluation,

2014