2-aminothiazole has been researched along with Alzheimer Disease in 5 studies
2-aminothiazole: RN given refers to parent cpd; structure
1,3-thiazol-2-amine : A primary amino compound that is 1,3-thiazole substituted by an amino group at position 2.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kilic, B | 2 |
| Bardakkaya, M | 2 |
| Ilıkcı Sagkan, R | 1 |
| Aksakal, F | 2 |
| Shakila, S | 2 |
| Dogruer, DS | 2 |
| Sagkan, RI | 1 |
| Huffman, SE | 1 |
| Yawson, GK | 1 |
| Fisher, SS | 1 |
| Bothwell, PJ | 1 |
| Platt, DC | 1 |
| Jones, MA | 1 |
| Hamaker, CG | 1 |
| Webb, MI | 1 |
| Lagoja, I | 1 |
| Pannecouque, C | 1 |
| Griffioen, G | 1 |
| Wera, S | 1 |
| Rojasdelaparra, VM | 1 |
| Van Aerschot, A | 1 |
| Helal, CJ | 1 |
| Sanner, MA | 1 |
| Cooper, CB | 1 |
| Gant, T | 1 |
| Adam, M | 1 |
| Lucas, JC | 1 |
| Kang, Z | 1 |
| Kupchinsky, S | 1 |
| Ahlijanian, MK | 1 |
| Tate, B | 1 |
| Menniti, FS | 1 |
| Kelly, K | 1 |
| Peterson, M | 1 |
5 other studies available for 2-aminothiazole and Alzheimer Disease
| Article | Year |
|---|---|
New thiourea and benzamide derivatives of 2-aminothiazole as multi-target agents against Alzheimer's disease: Design, synthesis, and biological evaluation.
Topics: Acetylcholinesterase; Alzheimer Disease; Benzamides; Butyrylcholinesterase; Cholinesterase Inhibitor | 2023 |
Synthesis and evaluation of multitarget new 2-aminothiazole derivatives as potential anti-Alzheimer's agents.
Topics: Acetylcholinesterase; Alzheimer Disease; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; M | 2023 |
Ruthenium(iii) complexes containing thiazole-based ligands that modulate amyloid-β aggregation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line, Tumor; Cell Survival; Coordination Com | 2020 |
Substituted 2-aminothiazoles are exceptional inhibitors of neuronal degeneration in tau-driven models of Alzheimer's disease.
Topics: Alzheimer Disease; Cell Line; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Bi | 2011 |
Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer's disease.
Topics: Alzheimer Disease; Amides; CDC2-CDC28 Kinases; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 5; | 2004 |