2-aminopyrimidine has been researched along with Leukemia, Myeloid, Acute in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 5 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gu, YC; Han, L; Hou, Y; Li, C; Liu, Y; Meng, J; Shi, X; Tong, M; Wang, C; Wen, J; Xu, S; Zhao, Y; Zhu, Y; Zhu, Z | 1 |
| Deng, X; Hu, Y; Ling, Y; Liu, Y; Ran, F; Tao, W; Wu, H; Xie, X; Zhang, Y; Zhu, J | 1 |
| Hu, X; Jin, T; Li, J; Li, X; Liu, T; Shen, L; Tong, L; Wang, C; Wang, P; Xu, R; Zhou, Y | 1 |
| Gao, Y; Li, J; Li, X; Lian, X; Liu, T; Tong, L; Wang, P; Zhou, Y | 1 |
| Jiang, K; Jin, T; Li, J; Liu, T; Long, X; Song, P; Wang, P; Wu, W; Xu, G; Zhou, Y | 1 |
5 other study(ies) available for 2-aminopyrimidine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
2-Aminopyrimidine derivatives as selective dual inhibitors of JAK2 and FLT3 for the treatment of acute myeloid leukemia.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; fms-Like Tyrosine Kinase 3; Humans; Janus Kinase 2; Leukemia, Myeloid, Acute; Microsomes, Liver; Protein Kinase Inhibitors; Rats; Structure-Activity Relationship | 2023 |
Design, synthesis and pharmacological characterization of aminopyrimidine derivatives as BTK/FLT3 dual-target inhibitors against acute myeloid leukemia.
Topics: Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Protein Kinase Inhibitors; Pyrimidines | 2023 |
Discovery of 2-Aminopyrimidine Derivatives as Potent Dual FLT3/CHK1 Inhibitors with Significantly Reduced hERG Inhibitory Activities.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Mice; Mutation; Protein Kinase Inhibitors; Pyrimidines | 2023 |
Design, synthesis and biological evaluation of 2-aminopyrimidine derivatives as potent FLT3 inhibitors.
Topics: Apoptosis; Cell Line, Tumor; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Mutation; Protein Kinase Inhibitors | 2023 |
Design, Synthesis, and Biological Evaluation of Orally Bioavailable CHK1 Inhibitors Active against Acute Myeloid Leukemia.
Topics: Administration, Oral; Animals; Binding Sites; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 1; DNA Repair; Drug Design; Drug Screening Assays, Antitumor; Drug Stability; Half-Life; Humans; Leukemia, Myeloid, Acute; Mice; Molecular Docking Simulation; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2021 |