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2-aminopurine and Disease Models, Animal

2-aminopurine has been researched along with Disease Models, Animal in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (20.00)18.2507
2000's11 (55.00)29.6817
2010's3 (15.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Adriaenssens, E; Amand, S; Bailly, C; Benhabiles, H; Chassat, T; Copin, MC; Duvernois-Berthet, E; Guilbert, R; Hannebique, D; Kulozik, A; Lejeune, F; Leroy, C; Marchand, V; Moreau, PA; Motorin, Y; Mouray, A; Rebuffat, S; Saliou, JM; Trzaska, C; Tulasne, D; Werkmeister, E; Westhof, E1
Chen, Y; Pan, Y; Qin, Y; Xiang, R; Yang, J; Yang, SY; Zheng, M; Zhong, L; Zhou, S1
Fukuda, M; Higaki, S; Komoto, S; Shimomura, Y1
Haneji, T; Nagata, T; Okamura, H; Shinohara, H; Teramachi, J; Yang, D1
Edden, Y; Hartshtark, Z; Ilan, L; Khalaileh, A; Kolodkin-Gal, D; Panet, A; Pikarsky, AJ; Pikarsky, E; Rabkin, SD; Zamir, G1
Jarisch, J; Smith, AL; Watson, ME1
Oyston, PCF; Taylor, VL; Titball, RW1
Biswas, S; Field, HJ; Jennens, L1
Maung, M; Slomka, MJ; Tsiquaye, KN1
Field, HJ; Thackray, AM2
Färber, I; Ulbricht, A; Wutzler, P1
Main, J; McCarron, B; Thomas, HC1
Cote, P; Gerin, JL; Hornbuckle, W; Korba, BE; Schinazi, R; Tennant, BC1
Benfield, DA; Guanghua, L; Kim, TS; Lawson, SR; Robinson, B; Rowland, RR; Stefanick, J1
Higaki, S; Hill, JM; Kesavan, P; Loutsch, JM; Marquart, ME; Sainz, B; Tal-Singer, R; Zheng, X1
Chen, Y; Guo, S; Huang, A; Qi, Z1
Bang, D; Kwon, HJ; Lee, ES; Lee, S; Lee, SI; Sohn, S1
Field, HJ; Gürr, WK; Littler, E; Shaw, MM; Thackray, AM; Watts, PA1

Reviews

1 review(s) available for 2-aminopurine and Disease Models, Animal

ArticleYear
Treatment of chronic viral hepatitis.
    Antiviral chemistry & chemotherapy, 1998, Volume: 9, Issue:6

    Topics: 2-Aminopurine; Animals; Antimetabolites; Antiviral Agents; Carcinoma, Hepatocellular; Disease Models, Animal; Drug Therapy, Combination; Ducks; Famciclovir; Female; Hepatitis B, Chronic; Hepatitis C, Chronic; Hepatitis, Animal; Humans; Immunologic Factors; Interferon-alpha; Lamivudine; Liver Cirrhosis; Liver Neoplasms; Male; Marmota; Poultry Diseases; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured

1998

Other Studies

19 other study(ies) available for 2-aminopurine and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations.
    Nature communications, 2020, 03-20, Volume: 11, Issue:1

    Topics: 2-Aminopurine; Animals; Codon, Nonsense; Disease Models, Animal; Drug Discovery; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Genes, p53; HEK293 Cells; HeLa Cells; Humans; Lepisma; Mice; Mice, Nude; Mutation; RNA, Transfer; tRNA Methyltransferases

2020
A preclinical evaluation of SKLB261, a multikinase inhibitor of EGFR/Src/VEGFR2, as a therapeutic agent against pancreatic cancer.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:2

    Topics: 2-Aminopurine; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Evaluation, Preclinical; ErbB Receptors; Female; G1 Phase; Humans; Mice, Nude; Neoplasm Metastasis; Pancreatic Neoplasms; Piperazines; Protein Kinase Inhibitors; Rats, Sprague-Dawley; Recombinant Proteins; Resting Phase, Cell Cycle; Signal Transduction; src-Family Kinases; Vascular Endothelial Growth Factor Receptor-2; Zebrafish

2015
Effects of antiviral medications on herpetic epithelial keratitis in mice.
    Japanese journal of ophthalmology, 2015, Volume: 59, Issue:3

    Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Administration, Topical; Animals; Antiviral Agents; Disease Models, Animal; DNA Copy Number Variations; DNA, Viral; Epithelium, Corneal; Eye Infections, Viral; Famciclovir; Female; Herpesvirus 1, Human; Keratitis, Herpetic; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Tears; Trigeminal Nerve; Valacyclovir; Valine

2015
Double Stranded RNA-Dependent Protein Kinase is Necessary for TNF-α-Induced Osteoclast Formation In Vitro and In Vivo.
    Journal of cellular biochemistry, 2015, Volume: 116, Issue:9

    Topics: 2-Aminopurine; Animals; Bone Resorption; Cell Differentiation; Cells, Cultured; Disease Models, Animal; eIF-2 Kinase; Gene Expression Regulation; In Vitro Techniques; Macrophages; Mice; Osteoclasts; Signal Transduction; Tumor Necrosis Factor-alpha

2015
Herpes simplex virus delivery to orthotopic rectal carcinoma results in an efficient and selective antitumor effect.
    Gene therapy, 2009, Volume: 16, Issue:7

    Topics: 2-Aminopurine; Adenocarcinoma; Animals; Antimetabolites; Apoptosis; Blotting, Western; Cell Line, Tumor; Cells, Cultured; Colonic Neoplasms; Disease Models, Animal; Drug Therapy, Combination; eIF-2 Kinase; Gene Transfer Techniques; Genes, Reporter; Genetic Vectors; Herpesvirus 1, Human; Humans; Injections, Intralesional; Luciferases; Male; Mice; Neoadjuvant Therapy; Oncolytic Virotherapy; Oncolytic Viruses; Phosphorylation; Rectal Neoplasms; Viral Tropism; Virus Replication

2009
Inactivation of deoxyadenosine methyltransferase (dam) attenuates Haemophilus influenzae virulence.
    Molecular microbiology, 2004, Volume: 53, Issue:2

    Topics: 2-Aminopurine; Adenosine Triphosphatases; Animals; Bacterial Proteins; Cell Line; Cytoplasm; Deoxyribonucleases, Type II Site-Specific; Disease Models, Animal; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; Endothelial Cells; Epithelial Cells; Gene Deletion; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genetic Complementation Test; Haemophilus Infections; Haemophilus influenzae; Humans; Mutagenesis, Insertional; MutS DNA Mismatch-Binding Protein; Rats; Site-Specific DNA-Methyltransferase (Adenine-Specific); Virulence

2004
Oral immunization with a dam mutant of Yersinia pseudotuberculosis protects against plague.
    Microbiology (Reading, England), 2005, Volume: 151, Issue:Pt 6

    Topics: 2-Aminopurine; Animals; Anti-Bacterial Agents; Bacterial Vaccines; Bile Acids and Salts; Deoxyribonucleases, Type II Site-Specific; Disease Models, Animal; DNA, Bacterial; Female; Mice; Mice, Inbred BALB C; Oligonucleotide Array Sequence Analysis; Plague; Site-Specific DNA-Methyltransferase (Adenine-Specific); Survival Analysis; Vaccines, Attenuated; Virulence; Yersinia pestis; Yersinia pseudotuberculosis

2005
The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1.
    Antiviral research, 2007, Volume: 75, Issue:1

    Topics: 2-Aminopurine; Administration, Oral; Animals; Antiviral Agents; Brain Stem; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Ear; Famciclovir; Herpes Simplex; Herpesvirus 1, Human; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Mice, Nude; Pyridines; Skin; Sulfonamides; Thiazoles

2007
Oral famciclovir against duck hepatitis B virus replication in hepatic and nonhepatic tissues of ducklings infected in ovo.
    Journal of medical virology, 1994, Volume: 42, Issue:3

    Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Animals; Animals, Newborn; Antiviral Agents; Biotransformation; Disease Models, Animal; DNA, Viral; Ducks; Eggs; Famciclovir; Guanine; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Kidney; Liver; Organ Specificity; Pancreas; Poultry Diseases; Prodrugs; Spleen; Viremia; Virus Replication; Xanthine Oxidase

1994
Differential effects of famciclovir and valaciclovir on the pathogenesis of herpes simplex virus in a murine infection model including reactivation from latency.
    The Journal of infectious diseases, 1996, Volume: 173, Issue:2

    Topics: 2-Aminopurine; Acute Disease; Acyclovir; Animals; Antiviral Agents; Brain Stem; Disease Models, Animal; Ear, External; Famciclovir; Female; Ganglia, Spinal; Herpes Simplex; Herpesvirus 1, Human; Mice; Mice, Inbred BALB C; Prodrugs; Trigeminal Ganglion; Valacyclovir; Valine; Virus Activation; Virus Latency; Virus Replication

1996
Antiviral efficacies of famciclovir, valaciclovir, and brivudin in disseminated herpes simplex virus type 1 infection in mice.
    Intervirology, 1997, Volume: 40, Issue:1

    Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Disease Models, Animal; Famciclovir; Hepatitis, Animal; Herpes Zoster; Herpesvirus 1, Human; Liver; Mice; Mice, Inbred BALB C; Valacyclovir; Valine; Viral Plaque Assay; Virus Replication

1997
Effects of famciclovir and valacyclovir on herpes simplex virus type 1 infection, latency, and reactivation in mice: how dissimilar are study results?
    The Journal of infectious diseases, 2000, Volume: 181, Issue:4

    Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Disease Models, Animal; Famciclovir; Herpes Simplex; Herpesvirus 1, Human; Mice; Recurrence; Valacyclovir; Valine; Virus Latency

2000
Enhanced antiviral benefit of combination therapy with lamivudine and famciclovir against WHV replication in chronic WHV carrier woodchucks.
    Antiviral research, 2000, Volume: 45, Issue:1

    Topics: 2-Aminopurine; Animals; Antiviral Agents; Carrier State; Disease Models, Animal; Drug Therapy, Combination; Famciclovir; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Lamivudine; Marmota; Prodrugs; Reverse Transcriptase Inhibitors; Viremia; Virus Replication

2000
Inhibition of porcine reproductive and respiratory syndrome virus by interferon-gamma and recovery of virus replication with 2-aminopurine.
    Archives of virology, 2001, Volume: 146, Issue:3

    Topics: 2-Aminopurine; Animals; Animals, Newborn; Antiviral Agents; Blotting, Northern; Cell Line; Cell Nucleus; Disease Models, Animal; Dose-Response Relationship, Drug; eIF-2 Kinase; Fluorescence; Interferon-gamma; Lung; Lymph Nodes; Porcine Reproductive and Respiratory Syndrome; Porcine respiratory and reproductive syndrome virus; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Swine Diseases; Virus Replication

2001
Effect of famciclovir on herpes simplex virus type 1 corneal disease and establishment of latency in rabbits.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:7

    Topics: 2-Aminopurine; Acute Disease; Administration, Oral; Administration, Topical; Animals; Antiviral Agents; Corneal Diseases; Disease Models, Animal; Dose-Response Relationship, Drug; Famciclovir; Herpes Simplex; Herpesvirus 1, Human; Keratitis, Herpetic; Rabbits; Trifluridine; Trigeminal Ganglion; Viral Load; Virus Latency

2001
[Experimental study on the effect of combination therapy with lamivudine and famciclovir against duck hepatitis B virus in vivo].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2001, Volume: 9, Issue:4

    Topics: 2-Aminopurine; Animals; Antiviral Agents; Disease Models, Animal; DNA, Viral; Drug Therapy, Combination; Ducks; Famciclovir; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Lamivudine; Microbial Sensitivity Tests

2001
Experimental studies on the antiviral agent famciclovir in Behçet's disease symptoms in ICR mice.
    The British journal of dermatology, 2001, Volume: 145, Issue:5

    Topics: 2-Aminopurine; Animals; Antiviral Agents; Behcet Syndrome; Disease Models, Animal; Famciclovir; Herpes Simplex; Interleukin-2; Mice; Mice, Inbred ICR; Prodrugs; Recurrence; Reverse Transcriptase Polymerase Chain Reaction

2001
Temporal pattern of herpes simplex virus type 1 infection and cell death in the mouse brain stem: influence of guanosine nucleoside analogues.
    Journal of virological methods, 2002, Volume: 102, Issue:1-2

    Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Apoptosis; Brain Stem; Disease Models, Animal; DNA Fragmentation; Famciclovir; Female; Ganciclovir; Guanine; Herpes Simplex; Herpesvirus 1, Human; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Valacyclovir; Valine

2002