| "In order to develop novel compounds for topical use possessing antiallergic as well as antiinflammatory activities, a series of o-aminophenol derivatives bearing H1-antihistaminic structures were synthesized and their effects were investigated on lipid peroxidation in rat brain homogenates, antiinflammatory effection arachidonic acid- and 12-O-tetradecanoylphorbol-13- acetate-induced mouse ear edema and antiallergic effect on 48-h homologous passive cutaneous anaphylaxis in rats." | 3.69 | Synthesis and topical antiinflammatory and antiallergic activities of antioxidant o-aminophenol derivatives. ( Akahoshi, F; Fukaya, C; Kajii, M; Kuwahara, S; Sakaue, Y; Sugiura, M; Sugiyama, N; Yakumaru, H, 1994) |