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2-aminoethoxydiphenyl borate and Disease Models, Animal

2-aminoethoxydiphenyl borate has been researched along with Disease Models, Animal in 24 studies

2-aminoethoxydiphenyl borate: is a novel membrane-penetrable modulator and transient receptor potential channel blocker; structure in first source; do not confuse with 2-APB cpd
2-aminoethoxydiphenylborane : An organoboron compound that is diphenylborane in which the borane hydrogen is replaced by a 2-aminoethoxy group.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"The aim was to study the effects of boric acid (BA) and 2-aminoethoxydiphenyl borate (2-APB) on oxidative stress and inflammation in an experimental necrotizing enterocolitis (NEC) rat model."7.80Effects of boric acid and 2-aminoethoxydiphenyl borate on necrotizing enterocolitis. ( Akşit, H; Çelik, T; Korkut, O; Sunay, B; Yazıcı, S, 2014)
"The aim was to study the effects of boric acid (BA) and 2-aminoethoxydiphenyl borate (2-APB) on oxidative stress and inflammation in an experimental necrotizing enterocolitis (NEC) rat model."3.80Effects of boric acid and 2-aminoethoxydiphenyl borate on necrotizing enterocolitis. ( Akşit, H; Çelik, T; Korkut, O; Sunay, B; Yazıcı, S, 2014)
"Carvacrol (50 mg/kg) was injected once per day for 3 or 7 days after seizure."1.56The Transient Receptor Potential Melastatin 7 (TRPM7) Inhibitors Suppress Seizure-Induced Neuron Death by Inhibiting Zinc Neurotoxicity. ( Choi, BY; Choi, HC; Hong, DK; Jeong, JH; Kang, BS; Kang, DH; Kho, AR; Lee, SH; Lim, MS; Park, MK; Suh, SW, 2020)
"Instead, anoxia Ca(2+)-dependently activated various small/intermediate-conductance K(+) channels in WT neurons, which was less evident in Mecp2(-/y) neurons."1.36Impaired hippocampal Ca2+ homeostasis and concomitant K+ channel dysfunction in a mouse model of Rett syndrome during anoxia. ( Kron, M; Müller, M, 2010)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (12.50)29.6817
2010's17 (70.83)24.3611
2020's4 (16.67)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Qu, YQ1
Gordillo-Martinez, F1
Law, BYK1
Han, Y1
Wu, A1
Zeng, W1
Lam, WK1
Ho, C1
Mok, SWF1
He, HQ1
Wong, VKW1
Wang, R1
Stirling, DP1
Cummins, K1
Wayne Chen, SR1
Stys, P1
Hsu, WL1
Hsieh, YC1
Yu, HS1
Yoshioka, T1
Wu, CY1
Boyacı, MG1
Rakip, U1
Aslan, A1
Koca, HB1
Aslan, E1
Korkmaz, S1
Yıldızhan, S1
Parrau, D1
Ebensperger, G1
Herrera, EA1
Moraga, F1
Riquelme, RA1
Ulloa, CE1
Rojas, RT1
Silva, P1
Hernandez, I1
Ferrada, J1
Diaz, M1
Parer, JT1
Cabello, G1
Llanos, AJ1
Reyes, RV1
Yildar, M1
Aksit, H2
Korkut, O2
Ozyigit, MO1
Sunay, B2
Seyrek, K1
Kaymakçı, M1
Acar, M1
Burukoglu, D1
Kutlu, HM1
Shojaolsadati, P1
Cingi, C1
Bayar Muluk, N1
Ye, L1
Zeng, Q1
Ling, M1
Ma, R1
Chen, H1
Lin, F1
Li, Z1
Pan, L1
Jeong, JH1
Lee, SH1
Kho, AR1
Hong, DK1
Kang, DH1
Kang, BS1
Park, MK1
Choi, BY1
Choi, HC1
Lim, MS1
Suh, SW1
Kojima, A1
Fukushima, Y1
Ito, Y1
Ding, WG1
Kitagawa, H1
Matsuura, H1
Qian, W1
Zhao, C1
Li, D1
Dai, R1
Spray, DC1
Iglesias, R1
Shraer, N1
Suadicani, SO1
Belzer, V1
Hanstein, R1
Hanani, M1
Naziroğlu, M1
Uğuz, AC1
Ismailoğlu, Ö1
Çiğ, B1
Özgül, C1
Borcak, M1
Yazıcı, S1
Çelik, T1
Li, X2
Wang, X1
Wang, Y1
Huang, C1
Li, J2
Xiao, J1
Liang, D1
Zhao, H1
Liu, Y2
Zhang, H1
Lu, X1
Peng, L1
Chen, YH1
Kron, M1
Müller, M1
Zhu, H1
Bhattacharyya, BJ1
Lin, H1
Gomez, CM1
Lin, L1
Zhao, X1
Yan, W1
Qi, W1
Bingen, BO1
Askar, SF1
Schalij, MJ1
Kazbanov, IV1
Ypey, DL1
Panfilov, AV1
Pijnappels, DA1
Wolkowicz, PE1
Wu, HC1
Urthaler, F1
Ku, DD1
Nicoud, IB1
Knox, CD1
Jones, CM1
Anderson, CD1
Pierce, JM1
Belous, AE1
Earl, TM1
Chari, RS1
Pal, S1
Sun, D1
Limbrick, D1
Rafiq, A1
DeLorenzo, RJ1

Other Studies

24 other studies available for 2-aminoethoxydiphenyl borate and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
2-Aminoethoxydiphenylborane sensitizes anti-tumor effect of bortezomib via suppression of calcium-mediated autophagy.
    Cell death & disease, 2018, 03-02, Volume: 9, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagy; Boron Compounds; Bortezomib; Calcium; Carcinom

2018
Axoplasmic reticulum Ca(2+) release causes secondary degeneration of spinal axons.
    Annals of neurology, 2014, Volume: 75, Issue:2

    Topics: Animals; Axons; Bacterial Proteins; Boron Compounds; Caffeine; Calcium; Disease Models, Animal; Endo

2014
2-Aminoethyl diphenylborinate inhibits bleomycin-induced skin and pulmonary fibrosis via interrupting intracellular Ca
    Journal of dermatological science, 2021, Volume: 103, Issue:2

    Topics: Adult; Aged; Animals; Bleomycin; Boron Compounds; Calcium Signaling; Case-Control Studies; Cell Dedi

2021
Effects of 2-Aminoethyl Diphenylborinate, a Modulator of Transient Receptor Potential and Orai Channels in Subarachnoid Hemorrhage: An Experimental Study.
    World neurosurgery, 2019, Volume: 127

    Topics: Animals; Apoptosis; Basilar Artery; Boron Compounds; Disease Models, Animal; Male; Malondialdehyde;

2019
Store-operated channels in the pulmonary circulation of high- and low-altitude neonatal lambs.
    American journal of physiology. Lung cellular and molecular physiology, 2013, Apr-15, Volume: 304, Issue:8

    Topics: Altitude; Altitude Sickness; Animals; Animals, Newborn; Boron Compounds; Disease Models, Animal; Hem

2013
Protective effect of 2-aminoethyl diphenylborinate on acute ischemia-reperfusion injury in the rat kidney.
    The Journal of surgical research, 2014, Volume: 187, Issue:2

    Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Boron Compounds; Calcium Channel Agonists; Cr

2014
The Potential Protective Effects of 2-aminoethyl Diphenylborinate against Inner Ear Acoustic Trauma: Experimental Study Using Transmission and Scanning Electron Microscopy.
    The journal of international advanced otology, 2015, Volume: 11, Issue:1

    Topics: Animals; Boron Compounds; Disease Models, Animal; Ear, Inner; Hearing Loss, Noise-Induced; Microscop

2015
Inhibition of IP3R/Ca2+ Dysregulation Protects Mice From Ventilator-Induced Lung Injury
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Apoptosis; Boron Compounds; Calcium; Calcium Chelating Agents; Calcium Signaling; Carbachol

2021
The Transient Receptor Potential Melastatin 7 (TRPM7) Inhibitors Suppress Seizure-Induced Neuron Death by Inhibiting Zinc Neurotoxicity.
    International journal of molecular sciences, 2020, Oct-24, Volume: 21, Issue:21

    Topics: Animals; Biological Transport; Blood-Brain Barrier; Boron Compounds; Cymenes; Disease Models, Animal

2020
Transient Receptor Potential Canonical Channel Blockers Improve Ventricular Contractile Functions After Ischemia/Reperfusion in a Langendorff-perfused Mouse Heart Model.
    Journal of cardiovascular pharmacology, 2018, Volume: 71, Issue:4

    Topics: Animals; Boron Compounds; Calcium Channel Blockers; Calcium Signaling; Cardiotonic Agents; Disease M

2018
Mechanism of interleukin-1 receptor antagonist protection against myocardial ischaemia/reperfusion-induced injury.
    Archives of cardiovascular diseases, 2018, Volume: 111, Issue:10

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Boron Compounds; Calcium Signaling; Cells, Cultur

2018
Gap junction mediated signaling between satellite glia and neurons in trigeminal ganglia.
    Glia, 2019, Volume: 67, Issue:5

    Topics: Animals; Boron Compounds; Carbenoxolone; Cells, Cultured; Disease Models, Animal; Female; Flufenamic

2019
Role of TRPM2 cation channels in dorsal root ganglion of rats after experimental spinal cord injury.
    Muscle & nerve, 2013, Volume: 48, Issue:6

    Topics: Action Potentials; Animals; Boron Compounds; Calcium; Calcium Channels, L-Type; Cinnamates; Disease

2013
Effects of boric acid and 2-aminoethoxydiphenyl borate on necrotizing enterocolitis.
    Journal of pediatric gastroenterology and nutrition, 2014, Volume: 58, Issue:1

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Antioxidants; Boric Acids; Boron Compounds; Dis

2014
Inhibition of transient receptor potential melastatin 7 (TRPM7) channel induces RA FLSs apoptosis through endoplasmic reticulum (ER) stress.
    Clinical rheumatology, 2014, Volume: 33, Issue:11

    Topics: Animals; Apoptosis; Arthritis, Rheumatoid; Boron Compounds; Calpain; Caspase 3; Disease Models, Anim

2014
2-Aminoethoxydiphenyl borate, a inositol 1,4,5-triphosphate receptor inhibitor, prevents atrial fibrillation.
    Experimental biology and medicine (Maywood, N.J.), 2010, Volume: 235, Issue:7

    Topics: Adenosine Triphosphate; Animals; Atrial Fibrillation; Boron Compounds; Calcium; Cell Line; Disease M

2010
Impaired hippocampal Ca2+ homeostasis and concomitant K+ channel dysfunction in a mouse model of Rett syndrome during anoxia.
    Neuroscience, 2010, Nov-24, Volume: 171, Issue:1

    Topics: Analysis of Variance; Animals; Benzophenones; Biophysical Phenomena; Boron Compounds; Calcium; Chary

2010
Skeletal muscle IP3R1 receptors amplify physiological and pathological synaptic calcium signals.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Oct-26, Volume: 31, Issue:43

    Topics: Action Potentials; Animals; Boron Compounds; Calcium; Calcium Signaling; Calpain; Carbachol; Caspase

2011
Influence of Orai1 intervention on mouse airway epithelium reactions in vivo and in vitro.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2012, Volume: 108, Issue:2

    Topics: Animals; Boron Compounds; Bronchoalveolar Lavage; Calcium Channels; Cells, Cultured; Cytokines; Dise

2012
Prolongation of minimal action potential duration in sustained fibrillation decreases complexity by transient destabilization.
    Cardiovascular research, 2013, Jan-01, Volume: 97, Issue:1

    Topics: Action Potentials; Animals; Animals, Newborn; Boron Compounds; Cells, Cultured; Disease Models, Anim

2013
2-APB induces instability in rat left atrial mechanical activity.
    Journal of cardiovascular pharmacology, 2007, Volume: 49, Issue:5

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Analysis of Variance; Animals; Atrial Function, Le

2007
2-APB protects against liver ischemia-reperfusion injury by reducing cellular and mitochondrial calcium uptake.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Boron Compounds; Calcium; Calcium Channe

2007
Epileptogenesis induces long-term alterations in intracellular calcium release and sequestration mechanisms in the hippocampal neuronal culture model of epilepsy.
    Cell calcium, 2001, Volume: 30, Issue:4

    Topics: Animals; Boron Compounds; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Disease Models, An

2001