2-aminoadipic acid has been researched along with Lupus Nephritis in 2 studies
2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
2-aminoadipic acid : An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.
Lupus Nephritis: Glomerulonephritis associated with autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Lupus nephritis is histologically classified into 6 classes: class I - normal glomeruli, class II - pure mesangial alterations, class III - focal segmental glomerulonephritis, class IV - diffuse glomerulonephritis, class V - diffuse membranous glomerulonephritis, and class VI - advanced sclerosing glomerulonephritis (The World Health Organization classification 1982).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the preventive effects of a novel nonpolyglutamatable antifolate, MX-68, on two experimental murine models of systemic lupus erythematosus (SLE); NZBxNZW F1 (BWF1) mice and chronic graft-versus-host disease (GVHD) mice, in comparison with classical antifolate methotrexate (MTX)." | 3.69 | Preventive effect of a novel antifolate, MX-68, in murine systemic lupus erythematosus (SLE). ( Mihara, M; Moriya, Y; Takagi, N; Takeda, Y; Urakawa, K, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mihara, M | 2 |
| Takagi, N | 2 |
| Urakawa, K | 2 |
| Moriya, Y | 2 |
| Takeda, Y | 2 |
1 trial available for 2-aminoadipic acid and Lupus Nephritis
| Article | Year |
|---|---|
A novel antifolate, MX-68, inhibits the development of autoimmune disease in MRL/lpr mice.
Topics: 2-Aminoadipic Acid; Administration, Oral; Animals; Antigen-Antibody Complex; Autoantibodies; Autoimm | 1997 |
1 other study available for 2-aminoadipic acid and Lupus Nephritis
| Article | Year |
|---|---|
Preventive effect of a novel antifolate, MX-68, in murine systemic lupus erythematosus (SLE).
Topics: 2-Aminoadipic Acid; Age Factors; Animals; Autoantibodies; Blood Urea Nitrogen; Cholesterol; Chronic | 1997 |