2-aminoadipic acid has been researched along with Lupus Erythematosus, Systemic in 1 studies
2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
2-aminoadipic acid : An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.
Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the preventive effects of a novel nonpolyglutamatable antifolate, MX-68, on two experimental murine models of systemic lupus erythematosus (SLE); NZBxNZW F1 (BWF1) mice and chronic graft-versus-host disease (GVHD) mice, in comparison with classical antifolate methotrexate (MTX)." | 3.69 | Preventive effect of a novel antifolate, MX-68, in murine systemic lupus erythematosus (SLE). ( Mihara, M; Moriya, Y; Takagi, N; Takeda, Y; Urakawa, K, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mihara, M | 1 |
| Takagi, N | 1 |
| Urakawa, K | 1 |
| Moriya, Y | 1 |
| Takeda, Y | 1 |
1 other study available for 2-aminoadipic acid and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
Preventive effect of a novel antifolate, MX-68, in murine systemic lupus erythematosus (SLE).
Topics: 2-Aminoadipic Acid; Age Factors; Animals; Autoantibodies; Blood Urea Nitrogen; Cholesterol; Chronic | 1997 |