2-aminoadipic acid has been researched along with Inflammation in 2 studies
2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
2-aminoadipic acid : An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neuroinflammation is a contributory factor underlying the progressive nature of dopaminergic neuronal loss within the substantia nigra (SN) of Parkinson's disease (PD) patients, albeit the role of astrocytes in this process has been relatively unexplored to date." | 1.51 | L-alpha-aminoadipic acid restricts dopaminergic neurodegeneration and motor deficits in an inflammatory model of Parkinson's disease in male rats. ( Chiara Goisis, R; Harkin, A; Haverty, R; O'Neill, E, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| O'Neill, E | 1 |
| Chiara Goisis, R | 1 |
| Haverty, R | 1 |
| Harkin, A | 1 |
| Gao, YJ | 1 |
| Ji, RR | 1 |
2 other studies available for 2-aminoadipic acid and Inflammation
| Article | Year |
|---|---|
L-alpha-aminoadipic acid restricts dopaminergic neurodegeneration and motor deficits in an inflammatory model of Parkinson's disease in male rats.
Topics: 2-Aminoadipic Acid; Animals; Astrocytes; Corpus Striatum; Dopaminergic Neurons; Glial Fibrillary Aci | 2019 |
Light touch induces ERK activation in superficial dorsal horn neurons after inflammation: involvement of spinal astrocytes and JNK signaling in touch-evoked central sensitization and mechanical allodynia.
Topics: 2-Aminoadipic Acid; Analysis of Variance; Animals; Astrocytes; Citrates; Disease Models, Animal; Ede | 2010 |