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2-aminoadipic acid and Graft vs Host Disease

2-aminoadipic acid has been researched along with Graft vs Host Disease in 1 studies

2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
2-aminoadipic acid : An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.

Graft vs Host Disease: The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the GRAFT VS HOST REACTION.

Research Excerpts

ExcerptRelevanceReference
"We evaluated the preventive effects of a novel nonpolyglutamatable antifolate, MX-68, on two experimental murine models of systemic lupus erythematosus (SLE); NZBxNZW F1 (BWF1) mice and chronic graft-versus-host disease (GVHD) mice, in comparison with classical antifolate methotrexate (MTX)."3.69Preventive effect of a novel antifolate, MX-68, in murine systemic lupus erythematosus (SLE). ( Mihara, M; Moriya, Y; Takagi, N; Takeda, Y; Urakawa, K, 1997)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mihara, M1
Takagi, N1
Urakawa, K1
Moriya, Y1
Takeda, Y1

Other Studies

1 other study available for 2-aminoadipic acid and Graft vs Host Disease

ArticleYear
Preventive effect of a novel antifolate, MX-68, in murine systemic lupus erythematosus (SLE).
    International journal of immunopharmacology, 1997, Volume: 19, Issue:2

    Topics: 2-Aminoadipic Acid; Age Factors; Animals; Autoantibodies; Blood Urea Nitrogen; Cholesterol; Chronic

1997