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2-aminoadipic acid and Disease Exacerbation

2-aminoadipic acid has been researched along with Disease Exacerbation in 2 studies

2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
2-aminoadipic acid : An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.

Research Excerpts

ExcerptRelevanceReference
"Recently we reported that astroglial loss and subsequent gliogenesis in the dentate gyrus play a role in epileptogenesis following pilocarpine-induced status epilepticus (SE)."7.74Spatiotemporal characteristics of astroglial death in the rat hippocampo-entorhinal complex following pilocarpine-induced status epilepticus. ( Choi, KC; Choi, SY; Kang, TC; Kim, DS; Kim, DW; Kim, JE; Kwak, SE; Kwon, OS, 2008)
"Recently we reported that astroglial loss and subsequent gliogenesis in the dentate gyrus play a role in epileptogenesis following pilocarpine-induced status epilepticus (SE)."3.74Spatiotemporal characteristics of astroglial death in the rat hippocampo-entorhinal complex following pilocarpine-induced status epilepticus. ( Choi, KC; Choi, SY; Kang, TC; Kim, DS; Kim, DW; Kim, JE; Kwak, SE; Kwon, OS, 2008)
"Although epilepsy was well controlled upon treatment with pyridoxine, thiamine, phenytoin and carbamazepine since early infancy, both had developmental delay with prominent speech delay as children."1.38Variability of phenotype in two sisters with pyridoxine dependent epilepsy. ( Alfadhel, M; Coulter-Mackie, M; Sirrs, S; Stockler-Ipsiroglu, S; Struys, E; Szeitz, A; Waters, PJ, 2012)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, DS1
Kim, JE1
Kwak, SE1
Choi, KC1
Kim, DW1
Kwon, OS1
Choi, SY1
Kang, TC1
Alfadhel, M1
Sirrs, S1
Waters, PJ1
Szeitz, A1
Struys, E1
Coulter-Mackie, M1
Stockler-Ipsiroglu, S1

Other Studies

2 other studies available for 2-aminoadipic acid and Disease Exacerbation

ArticleYear
Spatiotemporal characteristics of astroglial death in the rat hippocampo-entorhinal complex following pilocarpine-induced status epilepticus.
    The Journal of comparative neurology, 2008, Dec-10, Volume: 511, Issue:5

    Topics: 2-Aminoadipic Acid; Animals; Astrocytes; Cell Death; Cell Proliferation; Convulsants; Disease Models

2008
Variability of phenotype in two sisters with pyridoxine dependent epilepsy.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2012, Volume: 39, Issue:4

    Topics: 2-Aminoadipic Acid; Disease Progression; Epilepsy; Female; Humans; Phenotype; Siblings; Young Adult

2012