2-aminoadipic acid has been researched along with Cirrhosis in 4 studies
2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
2-aminoadipic acid : An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The hallmark of fibrosis is an excessive accumulation of collagen, ultimately leading to organ failure." | 2.61 | Collagen cross-linking mediated by lysyl hydroxylase 2: an enzymatic battlefield to combat fibrosis. ( Bank, RA; Piersma, B, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piersma, B | 1 |
| Bank, RA | 3 |
| Yu, WQ | 1 |
| Eom, YS | 1 |
| Shin, JA | 1 |
| Nair, D | 1 |
| Grzywacz, SX | 1 |
| Grzywacz, NM | 1 |
| Craft, CM | 1 |
| Lee, EJ | 1 |
| van der Slot-Verhoeven, AJ | 2 |
| van Dura, EA | 2 |
| Attema, J | 1 |
| Blauw, B | 1 |
| Degroot, J | 1 |
| Huizinga, TW | 1 |
| Zuurmond, AM | 2 |
| De Groot, J | 1 |
1 review available for 2-aminoadipic acid and Cirrhosis
| Article | Year |
|---|---|
Collagen cross-linking mediated by lysyl hydroxylase 2: an enzymatic battlefield to combat fibrosis.
Topics: 2-Aminoadipic Acid; Animals; Collagen; Enzyme Inhibitors; Fibrosis; Humans; Hydroxylation; Procollag | 2019 |
3 other studies available for 2-aminoadipic acid and Cirrhosis
| Article | Year |
|---|---|
Reshaping the Cone-Mosaic in a Rat Model of Retinitis Pigmentosa: Modulatory Role of ZO-1 Expression in DL-Alpha-Aminoadipic Acid Reshaping.
Topics: 2-Aminoadipic Acid; Animals; Cell Death; Disease Models, Animal; Down-Regulation; Ependymoglial Cell | 2016 |
The type of collagen cross-link determines the reversibility of experimental skin fibrosis.
Topics: 2-Aminoadipic Acid; Animals; Bleomycin; Collagen; Female; Fibrosis; Humans; Matrix Metalloproteinase | 2005 |
Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: implications for collagen cross-linking and treatment of fibrosis.
Topics: 2-Aminoadipic Acid; Cells, Cultured; Chromatography, High Pressure Liquid; Collagen; Fibrosis; Gene | 2005 |