2-aminoadipic acid has been researched along with Charcot-Marie-Tooth Disease in 1 studies
2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
2-aminoadipic acid : An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.
Charcot-Marie-Tooth Disease: A hereditary motor and sensory neuropathy transmitted most often as an autosomal dominant trait and characterized by progressive distal wasting and loss of reflexes in the muscles of the legs (and occasionally involving the arms). Onset is usually in the second to fourth decade of life. This condition has been divided into two subtypes, hereditary motor and sensory neuropathy (HMSN) types I and II. HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. (Adams et al., Principles of Neurology, 6th ed, p1343)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, WY | 1 |
| Zhu, H | 1 |
| Shen, Y | 1 |
| Wan, YH | 1 |
| Tu, XD | 1 |
| Wu, WT | 1 |
| Tang, L | 1 |
| Zhang, HX | 1 |
| Lu, SY | 1 |
| Jin, XL | 1 |
| Fei, J | 1 |
| Wang, ZG | 1 |
1 other study available for 2-aminoadipic acid and Charcot-Marie-Tooth Disease
| Article | Year |
|---|---|
DHTKD1 Deficiency Causes Charcot-Marie-Tooth Disease in Mice.
Topics: 2-Aminoadipic Acid; Adipates; Animals; Charcot-Marie-Tooth Disease; Codon, Nonsense; Disease Models, | 2018 |