2-aminoadipic acid has been researched along with Autosomal Dominant Juvenile Parkinson Disease in 1 studies
2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
2-aminoadipic acid : An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neuroinflammation is a contributory factor underlying the progressive nature of dopaminergic neuronal loss within the substantia nigra (SN) of Parkinson's disease (PD) patients, albeit the role of astrocytes in this process has been relatively unexplored to date." | 1.51 | L-alpha-aminoadipic acid restricts dopaminergic neurodegeneration and motor deficits in an inflammatory model of Parkinson's disease in male rats. ( Chiara Goisis, R; Harkin, A; Haverty, R; O'Neill, E, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| O'Neill, E | 1 |
| Chiara Goisis, R | 1 |
| Haverty, R | 1 |
| Harkin, A | 1 |
1 other study available for 2-aminoadipic acid and Autosomal Dominant Juvenile Parkinson Disease
| Article | Year |
|---|---|
L-alpha-aminoadipic acid restricts dopaminergic neurodegeneration and motor deficits in an inflammatory model of Parkinson's disease in male rats.
Topics: 2-Aminoadipic Acid; Animals; Astrocytes; Corpus Striatum; Dopaminergic Neurons; Glial Fibrillary Aci | 2019 |