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2-aminoadipic acid and Astrocytosis

2-aminoadipic acid has been researched along with Astrocytosis in 3 studies

2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
2-aminoadipic acid : An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.

Research Excerpts

ExcerptRelevanceReference
"Ocular hypertension is an important risk factor for glaucoma."1.43α-Aminoadipic acid protects against retinal disruption through attenuating Müller cell gliosis in a rat model of acute ocular hypertension. ( Ding, J; Han, S; Hughes, G; Li, J; Luo, H; Ma, W; Meng, Z; Su, J; Wang, X; Wang, Y; Yin, Y, 2016)
"Kainic acid was injected into the vitreous humor of C57BL/6 mice to induce reactive gliosis and death of RGCs."1.37Inhibition of reactive gliosis attenuates excitotoxicity-mediated death of retinal ganglion cells. ( Chintala, SK; Ganesh, BS, 2011)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thangaraj, G1
Christophel, J1
Bachmann, G1
Greif, A1
Layer, PG1
Wang, X1
Su, J1
Ding, J1
Han, S1
Ma, W1
Luo, H1
Hughes, G1
Meng, Z1
Yin, Y1
Wang, Y1
Li, J1
Ganesh, BS1
Chintala, SK1

Other Studies

3 other studies available for 2-aminoadipic acid and Astrocytosis

ArticleYear
PEDF counteracts DL-α-aminoadipate toxicity and rescues gliotoxic damages in RPE-free chicken retinal explants.
    Experimental eye research, 2015, Volume: 134

    Topics: 2-Aminoadipic Acid; Acetylcholine; Acetylcholinesterase; Animals; Apoptosis; Caspase 3; Chick Embryo

2015
α-Aminoadipic acid protects against retinal disruption through attenuating Müller cell gliosis in a rat model of acute ocular hypertension.
    Drug design, development and therapy, 2016, Volume: 10

    Topics: 2-Aminoadipic Acid; Animals; Apoptosis; Disease Models, Animal; Ependymoglial Cells; Gliosis; Male;

2016
Inhibition of reactive gliosis attenuates excitotoxicity-mediated death of retinal ganglion cells.
    PloS one, 2011, Mar-31, Volume: 6, Issue:3

    Topics: 2-Aminoadipic Acid; Animals; Apoptosis; Gliosis; Glycosphingolipids; Immunohistochemistry; In Situ N

2011