2-aminoadipic acid has been researched along with Alzheimer Disease in 2 studies
2-Aminoadipic Acid: A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).
2-aminoadipic acid : An alpha-amino acid that is adipic acid bearing a single amino substituent at position 2. An intermediate in the formation of lysine.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, N | 1 |
| Mota, BC | 1 |
| Stead, L | 1 |
| Palmer, EOC | 1 |
| Lombardero, L | 1 |
| Rodríguez-Puertas, R | 1 |
| de Paola, V | 1 |
| Barnes, SJ | 1 |
| Sastre, M | 1 |
| Pulido, R | 1 |
| Jiménez-Escrig, A | 2 |
| Orensanz, L | 1 |
| Saura-Calixto, F | 1 |
2 other studies available for 2-aminoadipic acid and Alzheimer Disease
| Article | Year |
|---|---|
Pharmacological ablation of astrocytes reduces Aβ degradation and synaptic connectivity in an ex vivo model of Alzheimer's disease.
Topics: 2-Aminoadipic Acid; Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Cell Size; Dendri | 2021 |
Study of plasma antioxidant status in Alzheimer's disease.
Topics: 2-Aminoadipic Acid; Alzheimer Disease; Antioxidants; Apolipoproteins E; Biomarkers; Fluorescence Rec | 2005 |