2-amino-7-phosphonoheptanoic acid has been researched along with Nervous System Diseases in 4 studies
2-amino-7-phosphonoheptanoic acid: (D)-isomer active as an antagonist of N-methyl-D-aspartate excitation of central neurons; (L)-isomer inactive; RN given refers to cpd without isomeric designation
Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tonic-clonic seizures were induced by 225-450 mg/kg Quin." | 1.28 | Studies on the potential neurotoxic and convulsant effects of increased blood levels of quinolinic acid in rats with altered blood-brain barrier permeability. ( Castiglioni, M; Samanin, R; Stasi, MA; Vezzani, A; Weckermann, B; Wu, HQ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Millan, MH | 2 |
| Wardley-Smith, B | 2 |
| Dürmüller, N | 1 |
| Meldrum, BS | 2 |
| Vezzani, A | 1 |
| Stasi, MA | 1 |
| Wu, HQ | 1 |
| Castiglioni, M | 1 |
| Weckermann, B | 1 |
| Samanin, R | 1 |
| Halsey, MJ | 1 |
| Shinozaki, H | 1 |
1 review available for 2-amino-7-phosphonoheptanoic acid and Nervous System Diseases
| Article | Year |
|---|---|
Pharmacology of the glutamate receptor.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Antidepressive Agents; Azepines; | 1988 |
3 other studies available for 2-amino-7-phosphonoheptanoic acid and Nervous System Diseases
| Article | Year |
|---|---|
The high pressure neurological syndrome in genetically epilepsy prone rats: protective effect of 2-amino-7-phosphono heptanoate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atmospheric Pressure; Epilepsy; Female; Male; Myo | 1991 |
Studies on the potential neurotoxic and convulsant effects of increased blood levels of quinolinic acid in rats with altered blood-brain barrier permeability.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Blood-Brain Barrier; Cerebral Co | 1989 |
Studies on the role of the NMDA receptor in the substantia nigra pars reticulata and entopeduncular nucleus in the development of the high pressure neurological syndrome in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Catalepsy; G | 1989 |