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2-amino-7-phosphonoheptanoic acid and Nerve Degeneration

2-amino-7-phosphonoheptanoic acid has been researched along with Nerve Degeneration in 3 studies

2-amino-7-phosphonoheptanoic acid: (D)-isomer active as an antagonist of N-methyl-D-aspartate excitation of central neurons; (L)-isomer inactive; RN given refers to cpd without isomeric designation

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Whetsell, WO1
Schwarcz, R2
Couratier, P1
Hugon, J1
Sindou, P1
Vallat, JM1
Dumas, M1
McMaster, OG1
Baran, H1
Wu, HQ1
Du, F1
French, ED1

Other Studies

3 other studies available for 2-amino-7-phosphonoheptanoic acid and Nerve Degeneration

ArticleYear
The organotypic tissue culture model of corticostriatal system used for examining amino acid neurotoxicity and its antagonism: studies on kainic acid, quinolinic acid and (-) 2-amino-7-phosphonoheptanoic acid.
    Journal of neural transmission. Supplementum, 1983, Volume: 19

    Topics: 2-Amino-5-phosphonovalerate; Afferent Pathways; Amino Acids; Animals; Caudate Nucleus; Corpus Striat

1983
Cell culture evidence for neuronal degeneration in amyotrophic lateral sclerosis being linked to glutamate AMPA/kainate receptors.
    Lancet (London, England), 1993, Jan-30, Volume: 341, Issue:8840

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aged; Amino Acids; Amyotrophic La

1993
gamma-Acetylenic GABA produces axon-sparing neurodegeneration after focal injection into the rat hippocampus.
    Experimental neurology, 1993, Volume: 124, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminobutyrate Transaminase; Alkynes; Amino Acids; Aminocaproates; Ani

1993