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2-amino-7-phosphonoheptanoic acid and Hyperesthesia

2-amino-7-phosphonoheptanoic acid has been researched along with Hyperesthesia in 1 studies

2-amino-7-phosphonoheptanoic acid: (D)-isomer active as an antagonist of N-methyl-D-aspartate excitation of central neurons; (L)-isomer inactive; RN given refers to cpd without isomeric designation

Hyperesthesia: Increased sensitivity to cutaneous stimulation due to a diminished threshold or an increased response to stimuli.

Research Excerpts

ExcerptRelevanceReference
"Pretreatment with mexiletine (5-30 mg/kg i."1.30Comparable dose-dependent inhibition of AP-7 sensitive strychnine-induced allodynia and paw pinch-induced nociception by mexiletine in the rat. ( Hodge, E; Khandwala, H; Loomis, CW, 1997)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khandwala, H1
Hodge, E1
Loomis, CW1

Other Studies

1 other study available for 2-amino-7-phosphonoheptanoic acid and Hyperesthesia

ArticleYear
Comparable dose-dependent inhibition of AP-7 sensitive strychnine-induced allodynia and paw pinch-induced nociception by mexiletine in the rat.
    Pain, 1997, Volume: 72, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Animals; Dose-Response Relationship, Drug; Foot; Hyperesthesia; Male; M

1997