2-amino-7-phosphonoheptanoic acid has been researched along with Aura in 13 studies
2-amino-7-phosphonoheptanoic acid: (D)-isomer active as an antagonist of N-methyl-D-aspartate excitation of central neurons; (L)-isomer inactive; RN given refers to cpd without isomeric designation
| Excerpt | Relevance | Reference |
|---|---|---|
| "Bilateral intracerebroventricular infusion of dl-homocysteic acid (DL-HCA) (600 nmol on each side) to immature 12-day-old rats induced generalized clonic-tonic seizures, recurring frequently for at least 90 min, with a high rate of survival." | 7.70 | Behavioral and metabolic changes in immature rats during seizures induced by homocysteic acid: the protective effect of NMDA and non-NMDA receptor antagonists. ( Folbergrová, J; Haugvicová, R; Mares, P, 2000) |
| " Motor limbic seizures induced by pilocarpine, 380 mg/kg intraperitoneally, are prevented by prior injection into the substantia nigra, pars reticulata, or the entopeduncular nucleus, of 2-APH, 10 nmol or 10 pmol, respectively." | 4.77 | Anti-epileptic effects of focal micro-injection of excitatory amino acid antagonists. ( de Sarro, G; Meldrum, B; Millan, M; Patel, S, 1988) |
| "Bilateral intracerebroventricular infusion of dl-homocysteic acid (DL-HCA) (600 nmol on each side) to immature 12-day-old rats induced generalized clonic-tonic seizures, recurring frequently for at least 90 min, with a high rate of survival." | 3.70 | Behavioral and metabolic changes in immature rats during seizures induced by homocysteic acid: the protective effect of NMDA and non-NMDA receptor antagonists. ( Folbergrová, J; Haugvicová, R; Mares, P, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (23.08) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Slamberová, R | 1 |
| Mares, P | 2 |
| Raisinghani, M | 1 |
| Faingold, CL | 1 |
| Peterson, DW | 1 |
| Collins, JF | 1 |
| Bradford, HF | 1 |
| Faingold, C | 1 |
| Casebeer, D | 1 |
| Folbergrová, J | 1 |
| Haugvicová, R | 1 |
| Cook, CJ | 1 |
| Devine, CE | 1 |
| Tavener, A | 1 |
| Gilbert, KV | 1 |
| De Sarro, G | 2 |
| Meldrum, BS | 2 |
| De Sarro, A | 1 |
| Patel, S | 2 |
| Gale, K | 1 |
| Zhong, P | 1 |
| Miller, LP | 1 |
| Murray, TF | 1 |
| Watson, GB | 2 |
| Lanthorn, TH | 2 |
| Millan, MH | 1 |
| Wardley-Smith, B | 1 |
| Dürmüller, N | 1 |
| Peeters, BW | 1 |
| van Rijn, CM | 1 |
| Vossen, JM | 1 |
| Coenen, AM | 1 |
| Rader, RK | 1 |
| Meldrum, B | 1 |
| Millan, M | 1 |
1 review available for 2-amino-7-phosphonoheptanoic acid and Aura
| Article | Year |
|---|---|
Anti-epileptic effects of focal micro-injection of excitatory amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Amino Acids; Animals; Anticonvulsants; Disease Su | 1988 |
12 other studies available for 2-amino-7-phosphonoheptanoic acid and Aura
| Article | Year |
|---|---|
Cortical epileptic afterdischarges in immature rats are differently influenced by NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Dizocilpine Maleate; Electric Stimulation; Ep | 2005 |
Evidence for the perirhinal cortex as a requisite component in the seizure network following seizure repetition in an inherited form of generalized clonic seizures.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Action Potentials; Analysis of Variance; Animals; | 2005 |
The kindled amygdala model of epilepsy: anticonvulsant action of amino acid antagonists.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Aminobutyrates; Amygdala; Animals; Anticonvulsants; Epilep | 1983 |
Modulation of the audiogenic seizure network by noradrenergic and glutamatergic receptors of the deep layers of superior colliculus.
Topics: 2-Amino-5-phosphonovalerate; Acoustic Stimulation; Adrenergic alpha-Agonists; Animals; Epilepsy; Exc | 1999 |
Behavioral and metabolic changes in immature rats during seizures induced by homocysteic acid: the protective effect of NMDA and non-NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Age Factors; Animals; Cerebral Cortex; Disease Models, Animal; Dizocilp | 2000 |
Contribution of amino acid transmitters to epileptiform activity and reflex suppression in electrically head stunned sheep.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Baclofen; Bicuculline; Blinking; | 1992 |
Excitatory neurotransmitters in the lateral habenula and pedunculopontine nucleus of rat modulate limbic seizures induced by pilocarpine.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Behavior, Animal; Electroencepha | 1992 |
Amino acid neurotransmitter interactions in 'area tempestas': an epileptogenic trigger zone in the deep prepiriform cortex.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Am | 1992 |
NMDA receptor antagonists attenuate a portion of the penicillin-induced epileptiform burst.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Epilepsy; Hippocampus; In Vitro | 1990 |
The high pressure neurological syndrome in genetically epilepsy prone rats: protective effect of 2-amino-7-phosphono heptanoate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atmospheric Pressure; Epilepsy; Female; Male; Myo | 1991 |
Involvement of NMDA receptors in non-convulsive epilepsy in WAG/Rij rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Brain; Disease Models, Animal; Dos | 1990 |
Epileptiform activity in vitro can produce long-term synaptic failure and persistent neuronal depolarization.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Amino Acids; Animals; Epilepsy; Hippocampus; In Vitr | 1989 |