2-amino-5-phosphonovalerate has been researched along with Uremia in 2 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| D'Hooge, R | 1 |
| Van de Vijver, G | 1 |
| Van Bogaert, PP | 1 |
| Marescau, B | 1 |
| Vanholder, R | 1 |
| De Deyn, PP | 1 |
| Woitzik, J | 1 |
| Abromeit, N | 1 |
| Daschner, M | 1 |
| Hömme, M | 1 |
| Vogel, M | 1 |
| Schaefer, F | 1 |
2 other studies available for 2-amino-5-phosphonovalerate and Uremia
| Article | Year |
|---|---|
Involvement of voltage- and ligand-gated Ca2+ channels in the neuroexcitatory and synergistic effects of putative uremic neurotoxins.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Calcium Cha | 2003 |
Hypothalamic release of nitric oxide and interaction with amino acid neurotransmitters in chronically uraemic rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Castration; Enzyme Inhibitors; Hypothalamus; Male; Microdialys | 2005 |