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2-amino-5-phosphonovalerate and Tremor

2-amino-5-phosphonovalerate has been researched along with Tremor in 6 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
" tremor, myoclonus and convulsions, successively appear, have been studied in fed and fasted rats with and without pretreatment with 2-amino-7-phosphonoheptanoic acid (180 mg/kg)."7.67The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats. ( Halsey, MJ; Meldrum, BS; Wardley-Smith, B, 1984)
" tremor, myoclonus and convulsions, successively appear, have been studied in fed and fasted rats with and without pretreatment with 2-amino-7-phosphonoheptanoic acid (180 mg/kg)."3.67The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats. ( Halsey, MJ; Meldrum, BS; Wardley-Smith, B, 1984)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's3 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wardley-Smith, B3
Meldrum, BS4
Halsey, MJ3
Meldrum, B1
Wardley-Smit, B1
Halsey, M1
Rostain, JC3
Pearce, PC1
Maclean, CJ1
Ward, EM1
Pearson, J1
Henley, M1
Darbin, O1
Risso, JJ1
Millan, MH1
Dürmüller, N1

Other Studies

6 other studies available for 2-amino-5-phosphonovalerate and Tremor

ArticleYear
The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats.
    Neuroscience letters, 1984, Jul-27, Volume: 48, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Brain; Fasti

1984
2-Amino-phosphonoheptanoic acid protects against the high pressure neurological syndrome.
    European journal of pharmacology, 1983, Mar-04, Volume: 87, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atmospheric Pressure; Epilepsies, Myoclonic; Male

1983
The orally active NMDA receptor antagonist CGP 39551 ameliorates the high pressure neurological syndrome in Papio anubis.
    Brain research, 1993, Sep-17, Volume: 622, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Administration, Oral; Animals; Anticonvulsants; Electroencephalography;

1993
The full expression of locomotor and motor hyperactivities induced by pressure requires both striatal dopaminergic and N-methyl-D-aspartate receptor activities in the rat.
    Neuroscience letters, 1999, Jun-04, Volume: 267, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Animals; Benzazepines; Corpus Striatum; Dopamine Antagonists; Dopamine

1999
The high pressure neurological syndrome in genetically epilepsy prone rats: protective effect of 2-amino-7-phosphono heptanoate.
    Experimental neurology, 1991, Volume: 112, Issue:3

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atmospheric Pressure; Epilepsy; Female; Male; Myo

1991
Effect of 2-aminophosphonoheptanoic acid on the EEG of rats exposed to high pressure.
    Undersea biomedical research, 1986, Volume: 13, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atmospheric Pressure; Central Nervous System Dise

1986