2-amino-5-phosphonovalerate has been researched along with Symptom Cluster in 4 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Systemic administration of kainic acid results in the development of a characteristic convulsive syndrome, accompanied by neuropathological alterations and loss of transmitter markers in some forebrain regions." | 7.68 | Protection from kainic acid neuropathological syndrome by NMDA receptor antagonists: effect of MK-801 and CGP 39551 on neurotransmitter and glial markers. ( Barnabei, O; Contestabile, A; Migani, P; Virgili, M, 1992) |
| " tremor, myoclonus and convulsions, successively appear, have been studied in fed and fasted rats with and without pretreatment with 2-amino-7-phosphonoheptanoic acid (180 mg/kg)." | 7.67 | The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats. ( Halsey, MJ; Meldrum, BS; Wardley-Smith, B, 1984) |
| "Systemic administration of kainic acid results in the development of a characteristic convulsive syndrome, accompanied by neuropathological alterations and loss of transmitter markers in some forebrain regions." | 3.68 | Protection from kainic acid neuropathological syndrome by NMDA receptor antagonists: effect of MK-801 and CGP 39551 on neurotransmitter and glial markers. ( Barnabei, O; Contestabile, A; Migani, P; Virgili, M, 1992) |
| " tremor, myoclonus and convulsions, successively appear, have been studied in fed and fasted rats with and without pretreatment with 2-amino-7-phosphonoheptanoic acid (180 mg/kg)." | 3.67 | The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats. ( Halsey, MJ; Meldrum, BS; Wardley-Smith, B, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wardley-Smith, B | 2 |
| Meldrum, BS | 2 |
| Halsey, MJ | 2 |
| Meldrum, B | 1 |
| Wardley-Smit, B | 1 |
| Halsey, M | 1 |
| Rostain, JC | 1 |
| Virgili, M | 1 |
| Migani, P | 1 |
| Contestabile, A | 1 |
| Barnabei, O | 1 |
| Millan, MH | 1 |
4 other studies available for 2-amino-5-phosphonovalerate and Symptom Cluster
| Article | Year |
|---|---|
The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Brain; Fasti | 1984 |
2-Amino-phosphonoheptanoic acid protects against the high pressure neurological syndrome.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atmospheric Pressure; Epilepsies, Myoclonic; Male | 1983 |
Protection from kainic acid neuropathological syndrome by NMDA receptor antagonists: effect of MK-801 and CGP 39551 on neurotransmitter and glial markers.
Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Epilepsy; Kainic Acid; Male; Neuroglia; N | 1992 |
Studies on the role of the NMDA receptor in the substantia nigra pars reticulata and entopeduncular nucleus in the development of the high pressure neurological syndrome in rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Catalepsy; G | 1989 |