2-amino-5-phosphonovalerate has been researched along with Stiff-Person Syndrome in 1 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Stiff-Person Syndrome: A condition characterized by persistent spasms (SPASM) involving multiple muscles, primarily in the lower limbs and trunk. The illness tends to occur in the fourth to sixth decade of life, presenting with intermittent spasms that become continuous. Minor sensory stimuli, such as noise and light touch, precipitate severe spasms. Spasms do not occur during sleep and only rarely involve cranial muscles. Respiration may become impaired in advanced cases. (Adams et al., Principles of Neurology, 6th ed, p1492; Neurology 1998 Jul;51(1):85-93)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiong, W | 1 |
| Chen, SR | 1 |
| He, L | 1 |
| Cheng, K | 1 |
| Zhao, YL | 1 |
| Chen, H | 1 |
| Li, DP | 1 |
| Homanics, GE | 1 |
| Peever, J | 1 |
| Rice, KC | 1 |
| Wu, LG | 1 |
| Pan, HL | 1 |
| Zhang, L | 1 |
1 other study available for 2-amino-5-phosphonovalerate and Stiff-Person Syndrome
| Article | Year |
|---|---|
Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Stem; Disease Models, Animal; Excitatory Amino | 2014 |