2-amino-5-phosphonovalerate has been researched along with Sclerosis in 5 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Sclerosis: A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Williamson, A | 2 |
| Spencer, D | 1 |
| Patrylo, PR | 1 |
| Spencer, DD | 1 |
| Kivi, A | 1 |
| Lehmann, TN | 2 |
| Kovács, R | 1 |
| Eilers, A | 1 |
| Jauch, R | 2 |
| Meencke, HJ | 1 |
| von Deimling, A | 1 |
| Heinemann, U | 2 |
| Gabriel, S | 2 |
| Golarai, G | 1 |
| Greenwood, AC | 1 |
| Feeney, DM | 1 |
| Connor, JA | 1 |
| Windmüller, O | 1 |
5 other studies available for 2-amino-5-phosphonovalerate and Sclerosis
| Article | Year |
|---|---|
Zinc reduces dentate granule cell hyperexcitability in epileptic humans.
Topics: 2-Amino-5-phosphonovalerate; Dentate Gyrus; Epilepsy, Temporal Lobe; Evoked Potentials; Humans; In V | 1995 |
Decrease in inhibition in dentate granule cells from patients with medial temporal lobe epilepsy.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Dentate Gyrus; Electric Conductiv | 1999 |
Effects of barium on stimulus-induced rises of [K+]o in human epileptic non-sclerotic and sclerotic hippocampal area CA1.
Topics: 2-Amino-5-phosphonovalerate; Adult; Barium Compounds; Bicuculline; Buffers; Chlorides; Electric Stim | 2000 |
Physiological and structural evidence for hippocampal involvement in persistent seizure susceptibility after traumatic brain injury.
Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Injuries; Cell Count; Cell Death; Chronic Disease; Denta | 2001 |
Effects of barium, furosemide, ouabaine and 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS) on ionophoretically-induced changes in extracellular potassium concentration in hippocampal slices from rats and from patients with epilepsy.
Topics: 2-Amino-5-phosphonovalerate; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anesthetics, Local; A | 2002 |