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2-amino-5-phosphonovalerate and Sclerosis

2-amino-5-phosphonovalerate has been researched along with Sclerosis in 5 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Sclerosis: A pathological process consisting of hardening or fibrosis of an anatomical structure, often a vessel or a nerve.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Williamson, A2
Spencer, D1
Patrylo, PR1
Spencer, DD1
Kivi, A1
Lehmann, TN2
Kovács, R1
Eilers, A1
Jauch, R2
Meencke, HJ1
von Deimling, A1
Heinemann, U2
Gabriel, S2
Golarai, G1
Greenwood, AC1
Feeney, DM1
Connor, JA1
Windmüller, O1

Other Studies

5 other studies available for 2-amino-5-phosphonovalerate and Sclerosis

ArticleYear
Zinc reduces dentate granule cell hyperexcitability in epileptic humans.
    Neuroreport, 1995, Jul-31, Volume: 6, Issue:11

    Topics: 2-Amino-5-phosphonovalerate; Dentate Gyrus; Epilepsy, Temporal Lobe; Evoked Potentials; Humans; In V

1995
Decrease in inhibition in dentate granule cells from patients with medial temporal lobe epilepsy.
    Annals of neurology, 1999, Volume: 45, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Dentate Gyrus; Electric Conductiv

1999
Effects of barium on stimulus-induced rises of [K+]o in human epileptic non-sclerotic and sclerotic hippocampal area CA1.
    The European journal of neuroscience, 2000, Volume: 12, Issue:6

    Topics: 2-Amino-5-phosphonovalerate; Adult; Barium Compounds; Bicuculline; Buffers; Chlorides; Electric Stim

2000
Physiological and structural evidence for hippocampal involvement in persistent seizure susceptibility after traumatic brain injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Nov-01, Volume: 21, Issue:21

    Topics: 2-Amino-5-phosphonovalerate; Animals; Brain Injuries; Cell Count; Cell Death; Chronic Disease; Denta

2001
Effects of barium, furosemide, ouabaine and 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS) on ionophoretically-induced changes in extracellular potassium concentration in hippocampal slices from rats and from patients with epilepsy.
    Brain research, 2002, Jan-18, Volume: 925, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anesthetics, Local; A

2002