2-amino-5-phosphonovalerate has been researched along with Sciatica in 2 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Sciatica: A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mutso, AA | 1 |
| Radzicki, D | 2 |
| Baliki, MN | 1 |
| Huang, L | 1 |
| Banisadr, G | 1 |
| Centeno, MV | 1 |
| Radulovic, J | 1 |
| Martina, M | 2 |
| Miller, RJ | 1 |
| Apkarian, AV | 1 |
| Pollema-Mays, SL | 1 |
| Sanz-Clemente, A | 1 |
2 other studies available for 2-amino-5-phosphonovalerate and Sciatica
| Article | Year |
|---|---|
Abnormalities in hippocampal functioning with persistent pain.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Biophysics; Bromodeoxyuridine; Conditioning, | 2012 |
Loss of M1 Receptor Dependent Cholinergic Excitation Contributes to mPFC Deactivation in Neuropathic Pain.
Topics: Acetylcholine; Action Potentials; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists | 2017 |