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2-amino-5-phosphonovalerate and Sciatica

2-amino-5-phosphonovalerate has been researched along with Sciatica in 2 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Sciatica: A condition characterized by pain radiating from the back into the buttock and posterior/lateral aspects of the leg. Sciatica may be a manifestation of SCIATIC NEUROPATHY; RADICULOPATHY (involving the SPINAL NERVE ROOTS; L4, L5, S1, or S2, often associated with INTERVERTEBRAL DISK DISPLACEMENT); or lesions of the CAUDA EQUINA.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mutso, AA1
Radzicki, D2
Baliki, MN1
Huang, L1
Banisadr, G1
Centeno, MV1
Radulovic, J1
Martina, M2
Miller, RJ1
Apkarian, AV1
Pollema-Mays, SL1
Sanz-Clemente, A1

Other Studies

2 other studies available for 2-amino-5-phosphonovalerate and Sciatica

ArticleYear
Abnormalities in hippocampal functioning with persistent pain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, Apr-25, Volume: 32, Issue:17

    Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Biophysics; Bromodeoxyuridine; Conditioning,

2012
Loss of M1 Receptor Dependent Cholinergic Excitation Contributes to mPFC Deactivation in Neuropathic Pain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017, 03-01, Volume: 37, Issue:9

    Topics: Acetylcholine; Action Potentials; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists

2017