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2-amino-5-phosphonovalerate and Peripheral Nervous System Diseases

2-amino-5-phosphonovalerate has been researched along with Peripheral Nervous System Diseases in 2 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.

Research Excerpts

ExcerptRelevanceReference
"Ankle inflammation was induced in rats by subcutaneous injection of complete Freund's adjuvant and the firing properties of spinal neurons receiving afferent input from the inflamed areas were studied four to six days later."1.29The burst-like firing of spinal neurons in rats with peripheral inflammation is reduced by an antagonist of N-methyl-D-aspartate. ( Duggan, AW; Grubb, BD; Hope, PJ; Pubols, L; Riley, RC, 1996)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grubb, BD1
Riley, RC1
Hope, PJ1
Pubols, L1
Duggan, AW1
Li, XY1
Wang, N1
Wang, YJ1
Zuo, ZX1
Koga, K1
Luo, F1
Zhuo, M1

Other Studies

2 other studies available for 2-amino-5-phosphonovalerate and Peripheral Nervous System Diseases

ArticleYear
The burst-like firing of spinal neurons in rats with peripheral inflammation is reduced by an antagonist of N-methyl-D-aspartate.
    Neuroscience, 1996, Volume: 74, Issue:4

    Topics: 2-Amino-5-phosphonovalerate; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Female;

1996
Long-term temporal imprecision of information coding in the anterior cingulate cortex of mice with peripheral inflammation or nerve injury.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Aug-06, Volume: 34, Issue:32

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cognition; Disease Models, Animal;

2014