2-amino-5-phosphonovalerate has been researched along with Pancreatitis in 2 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The current study examined spinal coadministration of low doses of NMDA receptor antagonist, D-(-)-2-Amino-5-phosphonovalerate (D-APV), and mu-opioid receptor agonist, morphine sulfate (MS), in reducing visceral nociception using an acute bradykinin induced pancreatitis model in rats." | 7.72 | Intrathecal coadministration of D-APV and morphine is maximally effective in a rat experimental pancreatitis model. ( Lu, Y; Vera-Portocarrero, LP; Westlund, KN, 2003) |
| " The current study examined spinal coadministration of low doses of NMDA receptor antagonist, D-(-)-2-Amino-5-phosphonovalerate (D-APV), and mu-opioid receptor agonist, morphine sulfate (MS), in reducing visceral nociception using an acute bradykinin induced pancreatitis model in rats." | 3.72 | Intrathecal coadministration of D-APV and morphine is maximally effective in a rat experimental pancreatitis model. ( Lu, Y; Vera-Portocarrero, LP; Westlund, KN, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lu, Y | 1 |
| Vera-Portocarrero, LP | 1 |
| Westlund, KN | 2 |
| Zhang, L | 1 |
| Zhang, X | 1 |
2 other studies available for 2-amino-5-phosphonovalerate and Pancreatitis
| Article | Year |
|---|---|
Intrathecal coadministration of D-APV and morphine is maximally effective in a rat experimental pancreatitis model.
Topics: 2-Amino-5-phosphonovalerate; Animals; Bradykinin; Disease Models, Animal; Drug Therapy, Combination; | 2003 |
Restoration of spontaneous exploratory behaviors with an intrathecal NMDA receptor antagonist or a PKC inhibitor in rats with acute pancreatitis.
Topics: Acute Disease; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; | 2004 |