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2-amino-5-phosphonovalerate and Pain, Postoperative

2-amino-5-phosphonovalerate has been researched along with Pain, Postoperative in 2 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Pain, Postoperative: Pain during the period after surgery.

Research Excerpts

ExcerptRelevanceReference
"We used a rat model of postoperative pain to investigate the effects of intra-RVM thalidomide treatments on postoperative pain, and evaluate the role of cannabinoid receptors in the effects of intra-RVM thalidomide treatments on GABAergic neurotransmission in the RVM neurons."1.48Administrations of thalidomide into the rostral ventromedial medulla produce antinociceptive effects in a rat model of postoperative pain. ( Gu, K; Jiang, B; Li, Y; Ma, P; Ma, X; Song, T; Wang, C; Yang, Y; Zhao, J, 2018)
"The effect of intrathecal L-NAME on mechanical hyperalgesia was also examined."1.30Lack of effect of intrathecally administered N-methyl-D-aspartate receptor antagonists in a rat model for postoperative pain. ( Brennan, TJ; Zahn, PK, 1998)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zahn, PK1
Brennan, TJ1
Song, T1
Ma, X1
Ma, P1
Gu, K1
Zhao, J1
Yang, Y1
Jiang, B1
Li, Y1
Wang, C1

Other Studies

2 other studies available for 2-amino-5-phosphonovalerate and Pain, Postoperative

ArticleYear
Lack of effect of intrathecally administered N-methyl-D-aspartate receptor antagonists in a rat model for postoperative pain.
    Anesthesiology, 1998, Volume: 88, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hypera

1998
Administrations of thalidomide into the rostral ventromedial medulla produce antinociceptive effects in a rat model of postoperative pain.
    Journal of neuroscience research, 2018, Volume: 96, Issue:2

    Topics: Analgesics; Animals; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists

2018