2-amino-5-phosphonovalerate has been researched along with Neoplasms in 2 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For the majority of tumors, expression levels of NR2B, GluR4, GluR6 and KA2 were lower compared to human brain tissue." | 1.35 | Expression of glutamate receptor subunits in human cancers. ( Brocke, KS; Gebhardt, C; Ikonomidou, C; Luksch, H; Marzahn, J; Rzeski, W; Sifringer, M; Staufner, C; Stepulak, A; Turski, L; Uckermann, O, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diamandis, P | 1 |
| Wildenhain, J | 1 |
| Clarke, ID | 1 |
| Sacher, AG | 1 |
| Graham, J | 1 |
| Bellows, DS | 1 |
| Ling, EK | 1 |
| Ward, RJ | 1 |
| Jamieson, LG | 1 |
| Tyers, M | 1 |
| Dirks, PB | 1 |
| Stepulak, A | 1 |
| Luksch, H | 1 |
| Gebhardt, C | 1 |
| Uckermann, O | 1 |
| Marzahn, J | 1 |
| Sifringer, M | 1 |
| Rzeski, W | 1 |
| Staufner, C | 1 |
| Brocke, KS | 1 |
| Turski, L | 1 |
| Ikonomidou, C | 1 |
2 other studies available for 2-amino-5-phosphonovalerate and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic | 2007 |
Expression of glutamate receptor subunits in human cancers.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Brain; Cell Line, Tumor; Excitatory Amino Acid Antagonists; Hu | 2009 |