2-amino-5-phosphonovalerate has been researched along with Necrosis in 8 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inoue, H | 1 |
| Okada, Y | 1 |
| Vanický, I | 1 |
| Marsala, M | 1 |
| Yaksh, TL | 1 |
| Lobner, D | 1 |
| Canzoniero, LM | 1 |
| Manzerra, P | 1 |
| Gottron, F | 1 |
| Ying, H | 1 |
| Knudson, M | 1 |
| Tian, M | 1 |
| Dugan, LL | 1 |
| Kerchner, GA | 1 |
| Sheline, CT | 1 |
| Korsmeyer, SJ | 1 |
| Choi, DW | 1 |
| Almeida, A | 1 |
| Bolaños, JP | 1 |
| Nargi-Aizenman, JL | 1 |
| Griffin, DE | 1 |
| Nellgård, B | 1 |
| Wieloch, T | 2 |
| Jensen, ML | 1 |
| Auer, RN | 1 |
8 other studies available for 2-amino-5-phosphonovalerate and Necrosis
| Article | Year |
|---|---|
Roles of volume-sensitive chloride channel in excitotoxic neuronal injury.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; Animals; Apoptosis; Benzothiadiazines; Bicuculline; Bu | 2007 |
Neurodegeneration induced by reversed microdialysis of NMDA; a quantitative model for excitotoxicity in vivo.
Topics: 2-Amino-5-phosphonovalerate; Animals; Corpus Striatum; Drug Combinations; Excitatory Amino Acid Agon | 1998 |
Zinc-induced neuronal death in cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Alleles; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Membrane; | 2000 |
A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.
Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Apoptosis; Carbonyl Cyanide p-Trifluor | 2001 |
Sindbis virus-induced neuronal death is both necrotic and apoptotic and is ameliorated by N-methyl-D-aspartate receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Animals; Apoptosis; Calcium; Cell Death; Cell Line; Cells, Cultured; Cr | 2001 |
Cerebral protection by AMPA- and NMDA-receptor antagonists administered after severe insulin-induced hypoglycemia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Brain Ischemia; Cell Death; Dizocilpine Maleat | 1992 |
Intraventricular infusion of 2-amino-7-phosphonoheptanoate (APH) mitigates ischaemic brain damage.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Brain Ischemia; Injections, Intraventricular; Mal | 1989 |
Hypoglycemia-induced neuronal damage prevented by an N-methyl-D-aspartate antagonist.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Caudate Nucleus; Electroencephalog | 1985 |