2-amino-5-phosphonovalerate has been researched along with Myoclonic Jerk in 8 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
| Excerpt | Relevance | Reference |
|---|---|---|
| " tremor, myoclonus and convulsions, successively appear, have been studied in fed and fasted rats with and without pretreatment with 2-amino-7-phosphonoheptanoic acid (180 mg/kg)." | 7.67 | The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats. ( Halsey, MJ; Meldrum, BS; Wardley-Smith, B, 1984) |
| " tremor, myoclonus and convulsions, successively appear, have been studied in fed and fasted rats with and without pretreatment with 2-amino-7-phosphonoheptanoic acid (180 mg/kg)." | 3.67 | The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats. ( Halsey, MJ; Meldrum, BS; Wardley-Smith, B, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wardley-Smith, B | 3 |
| Meldrum, BS | 3 |
| Halsey, MJ | 2 |
| Jaw, SP | 1 |
| Vuong, QT | 1 |
| Nguyen, M | 1 |
| Lai, YY | 1 |
| Siegel, JM | 1 |
| Darbin, O | 2 |
| Risso, JJ | 2 |
| Rostain, JC | 4 |
| Kriem, B | 1 |
| Abraini, JH | 1 |
| Millan, MH | 1 |
| Dürmüller, N | 1 |
8 other studies available for 2-amino-5-phosphonovalerate and Myoclonic Jerk
| Article | Year |
|---|---|
The high pressure neurological syndrome and 2-amino-7-phosphonoheptanoic acid: differences between fed and fasted rats.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Aspartic Acid; Atmospheric Pressure; Brain; Fasti | 1984 |
Effects of glutamate receptor antagonists on posthypoxic myoclonus in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Benzodiazepines; Binding, Competitive; Di | 1996 |
Brainstem-mediated locomotion and myoclonic jerks. II Pharmacological effects.
Topics: 2-Amino-5-phosphonovalerate; Animals; Basal Ganglia; Brain Stem; Cats; Corticotropin-Releasing Hormo | 1997 |
The full expression of locomotor and motor hyperactivities induced by pressure requires both striatal dopaminergic and N-methyl-D-aspartate receptor activities in the rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzazepines; Corpus Striatum; Dopamine Antagonists; Dopamine | 1999 |
High pressure enhanced NMDA activity in the striatum and the globus pallidus: relationships with myoclonia and locomotor and motor activity in rat.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Atmospheric Pressure; Corpus Striatum; Excita | 2000 |
Administration of either non-NMDA receptor agonists or NMDA receptor antagonists into the substantia nigra or the globus pallidus reduces the psychostimulant effect of high helium pressure on locomotor activity in rats.
Topics: 2-Amino-5-phosphonovalerate; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atmo | 1999 |
The high pressure neurological syndrome in genetically epilepsy prone rats: protective effect of 2-amino-7-phosphono heptanoate.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atmospheric Pressure; Epilepsy; Female; Male; Myo | 1991 |
Effect of 2-aminophosphonoheptanoic acid on the EEG of rats exposed to high pressure.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Atmospheric Pressure; Central Nervous System Dise | 1986 |