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2-amino-5-phosphonovalerate and Muscle Rigidity

2-amino-5-phosphonovalerate has been researched along with Muscle Rigidity in 1 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Turski, L1
Klockgether, T1
Turski, WA1
Schwarz, M1
Sontag, KH1

Other Studies

1 other study available for 2-amino-5-phosphonovalerate and Muscle Rigidity

ArticleYear
Blockade of excitatory neurotransmission in the globus pallidus induces rigidity and akinesia in the rat: implications for excitatory neurotransmission in pathogenesis of Parkinson's diseases.
    Brain research, 1990, Mar-26, Volume: 512, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Corpus Striatum; Dose-Response Relationship, Drug

1990