2-amino-5-phosphonovalerate has been researched along with Hypocalcemia in 1 studies
2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.
Hypocalcemia: Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Application of APV and nifedipine exacerbated low Mg(2+)-induced ILEs in the hippocampus but not the neocortex, indicating a distinct pharmacology for partial seizures of different brain regions." | 3.73 | Increased seizure susceptibility of the hippocampus compared with the neocortex of the immature mouse brain in vitro. ( Abdelmalik, PA; Burnham, WM; Carlen, PL, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abdelmalik, PA | 1 |
| Burnham, WM | 1 |
| Carlen, PL | 1 |
1 other study available for 2-amino-5-phosphonovalerate and Hypocalcemia
| Article | Year |
|---|---|
Increased seizure susceptibility of the hippocampus compared with the neocortex of the immature mouse brain in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Calcium Channel Blockers | 2005 |