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2-amino-5-phosphonovalerate and Hyperhomocysteinemia

2-amino-5-phosphonovalerate has been researched along with Hyperhomocysteinemia in 1 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Hyperhomocysteinemia: Condition in which the plasma levels of homocysteine and related metabolites are elevated (

Research Excerpts

ExcerptRelevanceReference
"Severe hyperhomocysteinemia (50-200 microM) often presents itself with acute neuronal dysfunction including seizures and psychosis."7.72Implications for hyperhomocysteinemia: not homocysteine but its oxidized forms strongly inhibit neuronal network activity. ( Fleischer, W; Görtz, P; Hoinkes, A; Otto, F; Schwahn, B; Siebler, M; Wendel, U, 2004)
"Severe hyperhomocysteinemia (50-200 microM) often presents itself with acute neuronal dysfunction including seizures and psychosis."3.72Implications for hyperhomocysteinemia: not homocysteine but its oxidized forms strongly inhibit neuronal network activity. ( Fleischer, W; Görtz, P; Hoinkes, A; Otto, F; Schwahn, B; Siebler, M; Wendel, U, 2004)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Görtz, P1
Hoinkes, A1
Fleischer, W1
Otto, F1
Schwahn, B1
Wendel, U1
Siebler, M1

Other Studies

1 other study available for 2-amino-5-phosphonovalerate and Hyperhomocysteinemia

ArticleYear
Implications for hyperhomocysteinemia: not homocysteine but its oxidized forms strongly inhibit neuronal network activity.
    Journal of the neurological sciences, 2004, Mar-15, Volume: 218, Issue:1-2

    Topics: Action Potentials; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Combinations; Dr

2004